This research links the Minnesota Multiphasic Personality Inventory-3 (MMPI-3), the most recent version of a frequently used test in clinical psychology practice, to a contemporary scientific model of mental health disorders. More specifically, the MMPI-3 scales can be approximately aligned with the recently introduced Hierarchical Taxonomy of Psychopathology (HiTOP).

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Documenting empirical correlates of the Minnesota Multiphasic Personality Inventory–3 (MMPI-3) scale scores is important for expanding the clinical utility of the instrument. To this end, the goals of the current study were to examine associations between scores on MMPI-3 scales and measures of anxiety sensitivity and distress intolerance, two constructs reflecting intolerance of negative emotional states that are implicated in many psychological conditions, and to identify the scales that most strongly predict each construct. Using a sample of 287 undergraduate students (71% women; Mage = 18.90, SD = 1.12; 85% White), zero-order correlational, regression, and dominance analyses were performed to address these goals. Results indicate that when MMPI-3 scale scores are considered conjointly by scale family, they predict meaningful variance in anxiety sensitivity and distress intolerance measure scores, with conceptually implicated scales offering the strongest prediction across scale families. Implications for both research and practice, limitations, and future research directions are discussed.