The Cloud computing emerges as a new computing paradigm which aims to provide reliable, customized and QoS guaranteed dynamic computing environments for end-users. In this paper, we study the Cloud computing paradigm from various aspects, such as definitions, distinct features, and enabling technologies. This paper brings an introductional review on the Cloud computing and provide the state-of-the-art of Cloud computing technologies.

Abstract-With the advent of Cloud computing, large-scale virtualized compute and data centers are becoming common in the computing industry. These distributed systems leverage commodity server hardware in mass quantity, similar in theory to many of the fastest Supercomputers in existence today. However these systems can consume a cities worth of power just to run idle, and require equally massive cooling systems to keep the servers within normal operating temperatures. This produces CO2 emissions and significantly contributes to the growing environmental issue of Global Warming. Green computing, a new trend for high-end computing, attempts to alleviate this problem by delivering both high performance and reduced power consumption, effectively maximizing total system efficiency. This paper focuses on scheduling virtual machines in a compute cluster to reduce power consumption via the technique of Dynamic Voltage Frequency Scaling (DVFS). Specifically, we present the design and implementation of an efficient scheduling algorithm to allocate virtual machines in a DVFS-enabled cluster by dynamically scaling the supplied voltages. The algorithm is studied via simulation and implementation in a multi-core cluster. Test results and performance discussion justify the design and implementation of the scheduling algorithm.

Knowledge of the genome-wide rate and spectrum of mutations is necessary to understand the origin of disease and the genetic variation driving all evolutionary processes. Here, we provide a genome-wide analysis of the rate and spectrum of mutations obtained in two Daphnia pulex genotypes via separate mutation-accumulation (MA) experiments. Unlike most MA studies that utilize haploid, homozygous, or self-fertilizing lines, D. pulex can be propagated ameiotically while maintaining a naturally heterozygous, diploid genome, allowing the capture of the full spectrum of genomic changes that arise in a heterozygous state. While base-substitution mutation rates are similar to those in other multicellular eukaryotes (about 4 × 10 −9 per site per generation), we find that the rates of large-scale (>100 kb) de novo copy-number variants (CNVs) are significantly elevated relative to those seen in previous MA studies. The heterozygosity maintained in this experiment allowed for estimates of gene-conversion processes. While most of the conversion tract lengths we report are similar to those generated by meiotic processes, we also find larger tract lengths that are indicative of mitotic processes. Comparison of MA lines to natural isolates reveals that a majority of large-scale CNVs in natural populations are removed by purifying selection. The mutations observed here share similarities with disease-causing, complex, large-scale CNVs, thereby demonstrating that MA studies in D. pulex serve as a system for studying the processes leading to such alterations.

Abstract-The notion of Cloud computing has not only reshaped the field of distributed systems but also fundamentally changed how businesses utilize computing today. While Cloud computing provides many advanced features, it still has some shortcomings such as the relatively high operating cost for both public and private Clouds. The area of Green computing is also becoming increasingly important in a world with limited energy resources and an ever-rising demand for more computational power. In this paper a new framework is presented that provides efficient green enhancements within a scalable Cloud computing architecture. Using power-aware scheduling techniques, variable resource management, live migration, and a minimal virtual machine design, overall system efficiency will be vastly improved in a data center based Cloud with minimal performance overhead.

Abstract-As Cloud computing emerges as a dominant paradigm in distributed systems, it is important to fully understand the underlying technologies that make clouds possible. One technology, and perhaps the most important, is virtualization. Recently virtualization, through the use of hypervisors, has become widely used and well understood by many. However, there are a large spread of different hypervisors, each with their own advantages and disadvantages. This manuscript provides an in-depth analysis of some of today's commonly accepted virtualization technologies from feature comparison to performance analysis, focusing on the applicability to High Performance Computing environments using FutureGrid resources. The results indicate virtualization sometimes introduces slight performance impacts depending on the hypervisor type, however the benefits of such technologies are profound and not all virtualization technologies are equal.