The widespread poor agricultural practices and ancient technologies continuously aggravate erosion of sediments and soil nutrients from delicate terrains at the major catchments of water shades. The ongoing study is assessing soil and nutrient losses in the four major land use covers (forest, pasture, tea and maize farms) in the upper catchment of Nyondo River Basin. The study sites in the upper catchment of Nyondo River Basin are densely populated and receive bimodal rains that support agriculture which is the main economic activity supporting livelihoods of the communities in the region. The experiment is laid in a randomized complete block design (RCBD) with each of the land use covers replicated 3 times with erosion traps mounted on 150 m2 plots. First data set was collected during the short rainy season of 2019 and long rainy season of 2020, with subsequent data collection continuing up to the short rainy season of 2021. Preliminary results showed that soil and nutrients were significantly lost in maize fields (p=0.05), forest cover was the least vulnerable while pasture cover had the highest surface runoff. Nutrient concentrations in the eroded sediments (p=0.05) were significantly higher than those that remained in maize plot while forest and tea fields registered comparable effectiveness in reducing both soil and nutrient losses, seasons notwithstanding. Pasture and maize fields had the highest water loss due to low infiltration rate and were also vulnerable to sediment and nutrients loss through surface runoff. The information will be used to inform and advise stake holders on land use policies geared towards attainment of sustainable agriculture and water quality in Nyondo and areas with similar landscapes and agricultural practices. Keywords: Erosion; Sediment; Nutrients; Land use