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1. Prevalence of increased platelet reactivity despite ASA treatment (ASA resistance) in patients treated surgically for carotid artery disease is high, suggesting a possibility of ineffective antiplatelet therapy. 2. A modest correlation between abnormal platelet response during treatment with ASA and the presence of unstable plaques suggests that these two phenomena may coexist but we were unable to show a clear association between them.

A decrease in carotid artery wall elasticity as measured using coefficient a may be associated with the process leading to the occurrence of restenosis after the surgery. Further research is required in order to confirm the conclusions presented in this paper and to explain potential mechanisms of this phenomenon.

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