Whether the anticancer activity of Gambogic acid is achieved by regulating cellular metabolic process remains unclear. Here we reported that Gambogic acid suppresses PPP pathway by covalently inhibiting 6PGD protein....
Most of the known senolytics are anti-cancer drugs or their derivative molecules. However, senolytics derived from the active ingredients of traditional Chinese medicine (TCM) are rarely reported. Here, we identified...
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