The Milken Institute is a nonprofit, nonpartisan think tank determined to increase global prosperity by advancing collaborative solutions that widen access to capital, create jobs, and improve health. We do this through independent, data-driven research, action-oriented meetings, and meaningful policy initiatives. ABOUT THE CENTER FOR STRATEGIC PHILANTHROPYThe Milken Institute Center for Strategic Philanthropy (CSP) designs smart giving strategies to accelerate philanthropic goals and progress. It is focused on maximizing the return on philanthropic investment by ensuring that innovation used to address one social issue is translated to another, best practices and metrics guide new and existing giving programs, and resources are invested to optimize outcomes. CSP provides comprehensive, digestible information that helps donors evaluate research efforts and funding opportunities in various areas of health and medical research. Expert advisory boards, in-depth due diligence, and an objective framework for evaluation shapes its analysis. ACKNOWLEDGMENTSWe would like to acknowledge the S Family Foundation for supporting the work, and the artist, William C. from The I'm Still Here Foundation, for the cover image.