BACKGROUNDHearing loss in chronic kidney disease is believed to be of multifactorial aetiology. Associated hypertension and diabetes mellitus, use of ototoxic drugs, haemodialysis and the changes in metabolic parameters are the various reasons implicated in hearing loss. Also, the prevalence, degree and patterns of hearing loss associated with Chronic Kidney Disease (CKD) reported by various studies differ significantly.The current study was conducted to assess the degree and type of hearing loss in CKD patients and to find out the association of duration of disease, haemodialysis and certain blood parameters with hearing loss. MATERIALS AND METHODS70 consenting patients of age 20 -60 yrs. with Non-Syndromic Chronic Kidney Disease referred from Nephrology Department were divided into 2 groups of 35 each, those with hearing loss i.e. HL group and without hearing loss i.e. non-HL group. Their demographic details and duration of the disease were recorded. They were subjected to physical examination, blood investigations and pure tone audiometry. Both groups were studied on the basis of above parameters. RESULTSIn the HL group, most patients (54.3%) were shown to have mild degree of hearing loss and higher frequencies were mostly affected. In addition, there was a comparatively stronger association of hyponatraemia and hypokalaemia with HL group than with non-HL group. Mean duration of the disease and haemodialysis was higher in HL group than in non-HL group. CONCLUSIONThe patients of Chronic Kidney Disease have mild degree of hearing loss, mostly at higher frequencies. A longer duration of the disease and haemodialysis are directly related to the hearing loss. Nonetheless, low serum sodium and potassium has a stronger relation with hearing loss group than in non-hearing loss group.