International classification of diseases (ICD)-11 is expected to be operative on the first day of January 2022. The key principle in this revision is simplification of the coding structure, electronic tooling, along with incorporation of advancements that occurred over past 30 years, since the publication of ICD-10. For a classification of mental disorders, development of the ICD-11 has been the most global, multilingual, multidisciplinary, and participative revision process by far. Adoption of a life-span approach, incorporation of a dimensional approach, provision of consistent and systematically characterized information as per recent evidence, and culture-related guidance along with effort for destigmatization are the salient features of this revision. In this review, we highlighted the process of developing the clinical description and diagnostic guidelines (CDDG), discussed the new disorders that were added with rationale, and last described the salient features of disorder grouping, pointing the key changes from ICD-10.
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