Introduction: Visceral leishmaniasis (VL) is a zoonosis of great importance to public health and is considered a neglected disease by the World Health Organization. The disease has expanded and become more prevalent in urban areas in Brazil. Methods: Geospatial analyses were performed and thematic maps of the triad of the disease were produced for the study period (2003)(2004)(2005)(2006)(2007)(2008)(2009)(2010)(2011)(2012) in the urban area of the municipality of Rondonópolis in the midwestern State of Mato Grosso (MT), Brazil, TerraView 4.2.2 software was used for the analyses. Results: A total of 87.9% of the 186 confi rmed human cases of VL were cured. Children between the ages of 1 and 4 were the most affected. Registered deaths were predominant among adults aged 60 years or older. The urban area of the municipality consists of eight strata and 12 census districts include 237 neighborhoods. All sectors had confi rmed cases of VL. During the study period, human cases of the disease were recorded in 90 neighborhoods. The 23 deaths from the disease were distributed in 21 neighborhoods. Sandfl ies carrying the parasite were captured in 192 out of 200 neighborhoods evaluated for the presence of the VL vector. The presence of dogs carrying the parasite was confi rmed in, 140 out of 154 surveyed neighborhoods. Conclusions: The data demonstrated the endemic nature of VL, with a high percentage of infected children, a high distribution of canine infection, and a wide adaptation and dispersal of the vectors in the urban environment. These results, illustrate the process of urbanization of VL in the municipality of Rondonópolis, MT, Brazil.

Um estudo do rendimento do veneno de cobras corais brasileiras e seu uso na avaliação do soro antielapídico A study on venom yield of Brazilian coralsnakes and its use in the evaluation of antielapidic serum

Resumo: Os acidentes ofídicos representam grave problema de saúde pública nas regiões tropicais devido à sua elevada incidência e morbimortalidade, especialmente os causados por jararacas. O presente artigo teve por objetivo conhecer, por meio de revisão da literatura, as principais complicações dos acidentes botrópicos. Foi realizada uma revisão sistemática através da análise de artigos científicos sobre o tema, com artigos de revisão, originais e casos clínicos escritos nos idiomas português, inglês datados entre o período de 2004 a 2015. O veneno botrópico é uma mistura de peptídeos e proteínas farmacologicamente ativas, que induzem sintomas clássicos, aliado às frequentes infecções locais, trazendo diversas complicações a vítima. O veneno da jararaca fica armazenado no local da picada, causando forte lesão proteolítica com complicações locais como a dor, o edema, equimoses, bolhas, necrose, abscessos, celulite, erisipela, síndrome compartimental e déficit funcional e nas sistêmicas: a hemorragia, nefrotoxicidade, choque circulatório e insuficiência renal aguda. Palavras-chave: Acidentes com serpentes. Bothrops. Complicações.

Este artigo está licenciado sob forma de uma licença Creative Commons Atribuição 4.0 Internacional, que permite uso irrestrito, distribuição e reprodução em qualquer meio, desde que a publicação original seja corretamente citada. Results: Variability in venom components and in the ability to recognize such components was demonstrated by the antielapid serum. Based on the western-blotting technique, the antielapid serum from Ezequiel Dias Foundation was able to recognize most, but not all the components present in the analyzed venoms. Conclusions:The results suggest restricted efficacy of the antielapid serum, due to its limitations against species from the Amazon region, reinforcing the need for a review of intraspecific and interspecific studies of Micrurus venoms.

2020) The complete mitochondrial genome of the aquatic coralsnake Micrurus surinamensis (Reptilia, Serpentes, Elapidae), Mitochondrial DNA Part B, 5:1, 233-235, ABSTRACTIn this study, we report the first complete mitochondrial genome sequence of the Aquatic Coralsnake Micrurus surinamensis. The mitochondrial genome lengthis 17,375 bp, comprising 13 protein-coding genes, 2 rRNA (12S and 16S) and 22 tRNA, as well as two typical control regions. Phylogenetic analysis based upon 13 protein-coding genes showed clusters based on terrestrial and marine species. ARTICLE HISTORY