With the rapid expansion of battery-powered electric vehicles (BEVs) in the automotive industry, research interest in lightweight Al alloys as well as their casting processes and applications has increased considerably. The substitution of castable aluminum alloys with superior strengths and electrical conductivity for copper reduces the weight and size of electric induction motors, and improves the energy efficiency and driving range of the BEVs. The present article was intended to give a general introduction into the common cast Al aluminum alloys and their relevant processes, as well as to motivate the development of high strength and conductive Al alloys for the practical realization of Al applications in the motors of the BEVs. A number of cast alloy systems containing Cu, Si, Ni, Mg, Fe, and Ti were evaluated, in comparison to nanostructured wrought Al alloys. The conventional casting processes suitable for Al alloys, high pressure die casting, squeeze casting, and sand casting were described. Strengthening mechanisms including solid solution strengthening, precipitation strengthening, dislocation accumulation strengthening, and grain boundary strengthening were presented. The phenomenon of electrical conduction for Al alloys was outlined. The mechanical properties and electrical properties of the recently developed Al alloys for casting and deformation processes were comprehensively listed and critically reviewed in association with microstructural characteristics.

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Mechanical strengths and electrical conductivity are the very important engineering properties of lightweight aluminum (Al) alloys used in automobiles, especially for battery-powered electric vehicles (BEV). However, the main issue is that the mechanical properties and the electrical conductivity of Al alloys are mutually exclusive. This study aims to simultaneously improve both the tensile properties and the electrical conductivity of the squeeze as-cast Al-6wt% Si-3wt% Cu by modifying its microstructure with the addition of nickel (Ni) and strontium (Sr). In comparison to those of the alloy free of Sr and Ni, the additions of 0.03 wt.% Sr and 0.5 wt.% Ni in the Al-6Si-3Cu alloy significantly improved the ultimate tensile strength, yield strength and electrical conductivity. This was because the addition of Ni element, as a transition element, collaborated with Cu to form fine intermetallic Al-Cu-Ni phases for dispersion strengthening. Also, the modification of the Si morphology from micron needles to nanoparticles by the Sr addition enhanced both the strengths and electrical conductivity of the developed alloy.

Detection and characterization of biomolecular interactions, such as protein–protein interactions (PPIs), are critical to a fundamental understanding of biochemical processes, thus being a driver of innovation for drug discovery, clinical diagnostics, and protein engineering. Among the many sensor types used to probe PPIs, organic field-effect transistors are particularly desirable due to their unique features, including tunability, sensitivity, low-power requirements, and multi-parameter readouts. This work describes the development of a biosensor based on organic field-effect transistors, covalently functionalized at the surface with an engineered ubiquitin variant for the specific and sensitive detection of ubiquitin-specific protease 8 (USP8). The resulting sensor was carefully characterized to reveal both electronic and solid-state properties. The sensing platform showed high sensitivity (sub-nanomolar analyte concentrations) and selectivity for USP8 and robust performance that suggests that it may be highly tunable. The sensing system introduced in this work provides a detection method for PPIs, which constitutes a promising platform for advanced biotechnology applications.

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