In an unselected series of pediatric brain tumors, 56 of 60 long-term survivors--craniopharyngiomas and pituitary tumors excluded--were investigated and interviewed mean X = 10 (5-16) years after diagnosis. After this time, sequelae were stable and included cognitive (38%), motor (25%), visual (20%), hormonal (20%), and psychological-emotional (14%) dysfunction. Memory dysfunction was found in 22% of patients with normal intelligence. Moderate or severe disability, from combinations of these impairments, was found in 34%. Sixty-six percent had no or mild disability compatible with active life and employment. However, these patients less often were married or had children compared with a control group of healthy subjects. Moderate and severe disability was found in 48% of supra- and in 21% of infratentorial tumors, after radiotherapy (RT) in 55% vs. without RT in 18%. RT before 6 years of age caused subnormal IQ in all cases. The self-reported quality of life was not related to degree of disability. Patients with psychological-emotional sequelae self-evaluated their quality of life lower than did patients with other types of long-term sequelae.

Growth and neurodevelopment at 6, 10 and 18 months of age have been studied prospectively and longitudinally in a series of 17 children born to mothers who used benzodiazepines (BZD) in therapeutic doses as their only psychotropic drug throughout pregnancy. The results were compared with a group of 29 children born to mothers without any known use of psychotropic drugs. The BZD-exposed children caught up their low mean birth-weight, at an early stage, whereas the slightly decreased head circumference at birth remained at the same low level. In five infants, a pattern of craniofacial anomalies was found. Deviating neurodevelopmental and clinical symptoms and signs were common. The gross motor development was retarded at 6 and 10 months, but was nearly normal at 18 months. Impaired fine motor functions were found on all follow-up occasions. At 18 months, the most prominent finding was a delayed development of pincer grasp. The BZD-exposed children showed deviations in muscle tone and pattern of movements more frequently than children in the reference group. The study suggests that the use of BZD in therapeutic doses throughout pregnancy can have negative effects on the development of children up to 18 months of age. The long-term hazards cannot be evaluated from these results. A further follow-up at early school age is needed and is in progress.

The effect of the maternal use of benzodiazepines (BZD) on the fetus and the newborn infant has been studied in a representative series of 17 newborn infants (BZD group). The pregnancy and the perinatal period were characterized by 20 items. On the 2nd day of life, a neurologic investigation was performed and comprised a total of 38 items, subgrouped into items of reflexes/reactions, tonus, and other symptoms and signs. An optimum finding for each item was selected. The results were compared with a group of 21 newborns fetally exposed to psychotropic drugs other than BZD (drug group) and a reference group of 29 newborns with no known fetal exposure to drugs. Infants in the BZD group had a lower birth weight for birth length, as compared to both the drug group and the reference group. Significant differences in frequency of pre- and perinatal complications and in neuro-behavior between the BZD group and the reference group were found in all groups of items. We conclude that the use of BZD during pregnancy is associated with impaired intrauterine growth and an increased frequency of pre- and perinatal events. It affects the newborn infant neurologically mainly in the form of intoxication and withdrawal symptoms.

Material objects call to us and structure our being. They are not passive, while we are active—rather, they embroil us in their lives as much as we engage them. Hence, sociality is not solely a human function but necessarily involves environments and artefacts. The notion of material poetics is, in this sense, a mutually shaping matrix that affects social life and thought. This philosophy is explored through an encounter with a Malay house. The house is in many ways liminal—a place in which thought and image dwells. It is traditional, yet unique; it holds and expresses history, yet that history is elsewhere and legendary; is Malay but with Chinese decorations, which articulate hybridity; is specifically local, yet involved in national and international flows. It embraces both oscillation and direction. The house is made of wood. This paper takes up this element, showing how the wood not only shelters, but also leads us to venture out to a garden of trees and a dream of jungles where encounters with things, stories and myths subvert our normal categories and expectations. The house leads us places and clears things for us, leading us into a new social field.

This paper provides landmarks for the study of the historical development and current expansion of academic psychology and clinical psychology education in Australia and three countries of the Malay Archipelago (Indonesia, Malaysia, Singapore). It reviews literature on the history of clinical psychology, and information from universities and psychological associations, and includes an overview of the current providers and forms of psychology education programmes and their curricula. A critical analysis informed by cultural anthropology indicates that psychology has only to a small extent been adjusted to different cultural contexts, while ‘western’ models of the discipline remain dominant. The neglect of attention to culture in psychology and clinical psychology raises important questions about the future of the discipline in the tropical regions of Australia and the Malay Archipelago.