health-related quality of life (HRQOL), quality of well-being scale (QWB), World Health Organization quality of life instruments (WHOQOL-BREF).Słowa kluczowe: jakość życia w ujęciu zdrowia (HRQOL), kwestionariusze oceny (QWB), World Health Organization quality of life instruments (WHOQOL-BREF).

Introduction The aim of this article was to compare the 30-day morbidity after radical cystectomy comparing the prevalent Clavien-Dindo Classification (CDC) and the novel Comprehensive Complication Index (CCI). Additionally, we evaluated the correlation between particular clinical features and the severity of perioperative morbidity. Material and methods A total of 42 patients were included into the study (33 men and 9 women) who underwent open radical cystectomy (RC) with bilateral lymphadenectomy for bladder cancer. The selection of complications was based on groundbreaking research on morbidity after RC. The assessment of perioperative complications was performed using the CDC and then the CCI. Results The CCI was found to be a significant upgrade in capturing cumulative morbidity in comparison to the CDC when used as the only evaluational tool. Conclusions Using only the CDC may underestimate the severity of perioperative complications. Unfavorable clinical features e.g. older age, chronic kidney disease (CKD), persistent nodal (pN+) disease, prior abdominal and pelvic surgeries as well as smoking are of significant importance for the increase of the severity of perioperative complications.

To divide the types of aging (successful, usual and impaired), as well as factors affecting this process, the protective role of physical activity was discussed in the literature. It was emphasized that physical activity is also a very important protective factor for cognitive aging - mainly executive function and memory. The prefrontal cortex and hippocampus, i.e. the regions of the brain responsible for the control and course of cognitive processes, show susceptibility to stimulation, which is movement exercises, which are prevention of degenerative changes within the brain.