Background: Cervical cancer is one of the leading causes of death among women facing gynecological problems. It requires early detection by various screening methods. Aims and Objectives: The current research aimed to assess the diagnostic utility of pap smear cytology and visual inspection of acetic acid (VIA) as a screening test for various cervical lesions. Materials and Methods: The current prospective study was conducted on 210 non-pregnant women. Cervical pap smears were taken and reported according to the revised Bethesda system, 2014. VIA examination was also done, and any dense opaque aceto-white lesion observation near the squamo-columnar junction was reported as VIA positive. The findings of pap smear cytology and VIA were correlated with findings of histopathology. Results: Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy of pap smear cytology for the diagnosis of cervical lesions were found to be 90.16%, 85.22%, 89.43%, 86.2%, and 88.09%, respectively; while sensitivity, specificity, PPV, NPV, and diagnostic accuracy of VIA for the diagnosis of cervical lesions were found to be 88.37%, 55.55%, 76%, 75%, and 75.71%, respectively. Our study showed a substantial degree of agreement between pap smear cytology and histopathology for the diagnosis of cervical lesions with Cohen’s kappa value being 0.755. Conclusion: The current study revealed that pap smear and VIA have high sensitivity with good diagnostic accuracy for the detection of neoplastic cervical lesions, which indicate that they can be used as an efficient screening tool for the detection of cervical lesions in their earlier stages.

Background: The etiological agent for pandemic COVID-19 is severe acute respiratory syndrome corona virus 2. Hematological and biochemical parameters are the indicators of inflammation and coagulopathy. Aims and Objectives: The present study aimed to determine how effectively the hematological parameters and biochemical markers can help predict the severity of critically ill COVID-19 patients. Materials and Methods: The current retrospective cohort study was conducted among 200 COVID-19 patients admitted in the Sanjay Gandhi Memorial Hospital, Rewa, Madhya Pradesh, India. In our lab’s computerized system, certain hematological and biochemical parameters of the patients were retrieved and recorded. Receiver operating characteristics (ROC) curve analysis was done to evaluate the diagnostic accuracy of hematological and biochemical parameters. Results: Total leukocyte count (TLC), absolute lymphocyte count (ALC), neutrophil to lymphocyte ratio (NLR), D-dimer, and serum ferritin had a significant relationship with severity among ICU patients (P<0.05). ALC, D-dimer, and serum ferritin can be used to predict the severity of COVID patients with area under the ROC-AUC curve values of 0.717, 0.725, and 0.710, respectively. Platelet to lymphocyte ratio, lymphocyte to monocyte ratio, and C-reactive protein were not useful to predict the severity of COVID illness. Conclusion: Hb concentration, TLC, NLR, D-dimer, and serum ferritin were significantly raised in critically ill COVID patients. ROC curve analysis showed that ALC, serum ferritin, and D-dimer were able to predict the severity of COVID illness effectively. Conclusively, these parameters can be used to track the prognosis of patients.

Body donation is one of the sources of cadaver supply to medical colleges. The shortage of cadavers in medical institutes is the main problem of learning anatomy across India.  The current research aimed to assess the knowledge and attitude of the general public regarding body donation.A cross-sectional study had conducted on 1500 voluntary people visiting or working in SSMC, Rewa (M.P.). A well-structured paper-based questionnaire had prepared for the collection of data. Descriptive data had expressed as frequency counts (percentage). Chi-square test had done to analyze differences in the awareness and willingness for body donation between the male and female groups. The difference between the two groups had considered significant if p &#60; 0.05.35.07% of all the participants were unaware of body donation. Females were more unaware and uninterested in body donation. Among aware participants, 12.53% showed their willingness for body donation. The majority of them were motivated by medical professionals and the media. 87.47% were reluctant to donate their bodies because of various reasons like religious barriers, psychological anxiety, etc. We concluded that the majority of our study participants were unaware of body donation. Lack of awareness and social stigma are the main causes of deficiency of cadavers in medical institutes. To create awareness among the general public regarding body donation is the need of the hour. Maintaining an ample supply of cadavers to the undertraining medical students is of utmost importance for turning them into skillful doctors in the future.

Background: Prediabetes, diabetes, and their associated complications adversely affect women’s health worldwide. Women in the reproductive age group are more prone for developing diabetes and its associated complications such as gestational diabetes and infertility. Hence, it is the need of the hour to diagnose women at risk of pre-diabetes. Oxidative stress, ischemia, and hypoxia have been suggested as important factors in developing prediabetes and its sequels. Aims and Objectives: The present study aimed to study the association of serum ischemia-modified albumin (IMA), namely, a marker of oxidative stress, ischemia, and hypoxia with prediabetes in the women of reproductive age group. Materials and Methods: The present study was carried out in 50 females in the reproductive age group of 19–45 years. The study population was further sub-divided into two groups: Group I consisted of 25 prediabetic patients and Group II consisted of 25 healthy controls. Serum samples of the subjects were analyzed for serum IMA, blood sugar profile, and other routine biochemistry tests. Results: The present study showed that mean serum IMA was raised in prediabetic group as compared to healthy controls. The serum IMA also positively correlated with blood sugar profile. Conclusion: Increased serum IMA could be used as a biomarker for predicting prediabetes in females of reproductive age group. This, in turn, would be helpful in preventing the burden of various complications known to occur in the natural course of prediabetes and diabetes.