Chemotherapy and allogeneic stem cell transplant suppress the body’s immunity making them more prone to neutropenic sepsis, for which the patients have to be given broad-spectrum antibiotics. These antibiotics disrupt the well-organized colony of our intestinal microbiome creating dysbiosis. Dysbiosis makes the intestine a favorable platform for certain Gram-positive bacilli to proliferate which is <em>Clostridium difficile</em>. Traditional treatment requires the patient to take metronidazole, vancomycin, and probiotics. Recurrent <em>C. difficile </em>infection makes the traditional treatment a failure. Thus, fecal microbial transplant is the answer to recurrent <em>C. difficile.</em>