Introduction:Transthoracic guided fine needle aspiration cytology (FNAC) of clinically suspected lung tumors is an increasingly common procedure in diagnosis. Cytospin Smear and Cellblock preparations of available material are helpful in subtyping and confirming the diagnosis, and they can also be used for further studies, i.e., special stain and immunohistochemistry, etc.Aims and Objectives:This research was undertaken to study the technique of guided transthoracic lung FNAC of clinically suspected lung tumors and the establish role of FNAC smears, cytospin smears, and cellblocks in the detection and typing of neoplastic lung lesions and correlation.Materials and Methods:Guided FNAC was taken from 100 cases of clinically suspected lung tumor and FNAC smears, cytospin smears, and cellblocks of aspirated material were studied over a period of 2 years from September 2011 to September 2013.Results:The material adequacies were 80% in FNAC smears, 83% in cytospin smears, and 89% in cellblocks. Additional information supported by cytospin smear and cellblock was 3% and 9%, respectively. Architectural preservation was better in FNAC smears (85%) and cellblocks (73.03%) than that in cytospin smears (31.33%). Morphological preservation was better in FNAC smears (90%) and cellblocks (75.28%) than that in cytospin smears (14.46%). Diagnostic accuracy was increased in the cellblocks and cytospin smears.Conclusion:Cytospin smear was helpful when low cellular material was obtained, and the concomitant examination of cellblocks not only confirmed the diagnosis of malignancy but also helped in classifying the obtained material and allowed further study on the same.
This study is done to determining the Incidence and Prognostic factors with Histopathological findings and ER & PR status in Young Female (≤ 40 years of age) having breast malignancy. we studied total cases and cases in young female ≤ 40 years of Pathologically diagnosed breast malignancies with family history with observation of Prognostic factors (Age, Tumor size, type, histological grade, invasion, lymph node status and ER & PR status) during one year (from august 2011 to august 2012). We observed total 88 cases of breast malignancies are in 1 year, out of them 22 cases are found in young female ≤ 40 years of age. So incidence of breast malignancies in young female is 25%. In 10 cases (45.45%) size of tumor is ≥ 5 cm, 14 cases (63.63%) shows invasion and lymph node metastasis. 47.36 % cases are ER/PR negative. We conclude that incidence of Breast malignancies in young female (≤ 40 years of age) are increasing, while tumor of young age female found biologically aggressive as per Histopathological findings and ER & PR status.
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