Background: Wound healing depends upon a balance between general factors which include nutritional status of the patient and local factors. Assessment of wound healing in relation to nutritional status of the patients in common surgical conditions.Methods: 46 surgical patients admitted in S.R.N. Hospital, Motilal Nehru Medical College, Allahabad during the period from July 2017 to July 2018, were included. Clinical, anthropometric examination, assessment of wound healing and factors affecting wound healing was done.Results: The mean age of the males patients were 38 years and that of female 33 years. Out of 46 patients included in our study 71.74% were male and 28.26% were females, and among these 15.15% of male and 38.46% female were malnourished. Percentage of wound contraction was 11.38% among the healthy and 2.30% in malnourished group, while the percentage of infection was 14% and 13% among healthy males and female and 20% each for malnourished males and females. Loss of weight was 9.4% and 10.1% among healthy male and female and 6.54% and 7.5% for malnourished male and females. The percentage of wound disruption in our study was 9% among malnourished group.Conclusions: Wound infection and disruption collectively increased the mortality and morbidity significantly in patients of malnourished group. Socio economic status has indirect correlation with wound healing. Malnourishment has a definite effect on wound healing.

The present investigation was conducted at Agronomy Research Farm, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya (U.P.) during Rabi season of 2019-20. The experiment was laid out in Factorial Randomized block design with three replications keeping four fertility levels viz., 100% RDF-IF (150 kg/h), 125% RDF-IF (25% through FYM), 100% RDF + 25%RDN through FYM, 75%RDF-IF+25%RDN through FYM and four weed management practices Weedy Check, Weed free up to 60 days, Sulfosulfuron @ 30 g/h + Carfentazole @ 20 g/h, Clodinafoppropagynol(60 g) + metsulfuron(4 g)=(64 g/h). Results revealed that among fertility levels application of 125% RDF-IF (25% through FYM) and in weed management practices weed free followed by125% RDF-IF (25% through FYM)+Clodinafoppropagynol (60 g) + metsulfuron (4 g)=(64 g/h) a.i ha-1 proved as superior than other treatments with respect to weed population, nutrient loss by weed, dry matter accumulation in weed, was found with the application of 125% RDF-IF (25% through FYM) and weed free treatment combination.

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Background: It has been shown that there is a transient elevation of serum liver enzymes after laparoscopic surgeries and major causative factor seemed to be the CO2 pneumoperitoneum. In most of the cases, it does not have any clinical significance in the patient with normal preoperative liver function. However, in patients with deranged liver function, these changes can have great significance.Methods: The present study was designed to determine and compare changes in liver function tests and renal function test following laparoscopic cholecystectomy and open cholecystectomy. This study was conducted on 100 patients admitted to Swaroop Rani Nehru Hospital, Allahabad, India from August 2017 to January 2019 who were having symptomatic cholelithiasis with a history of either acute cholecystitis, biliary colic or chronic cholecystitis. All patients were investigated for complete liver function tests and renal function test including serum bilirubin, SGOT, SGPT, alkaline phosphatase, LDH, S. urea, S. creatinine, S. Na+, S. K+, S. Ca+ and urinary sodium (UNa+). The laboratory tests were carried out in the same laboratory using one type of instrument.Results: In open cholecystectomy, bilirubin decreased by 11% (p value equals 0.191) and remained decreased to the preoperative value on day 1 and day 7. While, laparoscopic cholecystectomy at 14 mmHg pressure, mean bilirubin decreases by 14% immediately postoperatively (p value equals 0.1733) and returns to normal level in 7 days. These changes are clinically insignificant and statistically insignificant.Conclusions: Enzyme elevations could mostly be attributed to the adverse effects of the pneumoperitoneum on the hepatic blood flow and renal blood flow and CO2 absorption in the blood. Though, these changes do not seem to be clinically significant, care should be taken before deciding to perform laparoscopic cholecystectomy. This study suggested that laparoscopic cholecystectomy is a safe operative procedure and have added advantages. The disturbances in the function of the kidney after laparoscopic cholecystectomy are self-limited and not associated with any morbidity in patients with a healthy kidney function.

Background: Severe skin or soft tissue (SST) infections can involve fascia planes, thereby constitution necrotizing fascitis. Such infections are characterized by extensive necrosis and systemic toxicity [1,2] . Early clinical diagnosis of necrotizing fascitis and superficial SST infection (erysipelas or cellulitis), may be difficult [3,4] . Method: At the time of admission a detailed clinical history were taken, clinical examination was done, patients were admitted and stabilized in emergency ward, aggressive debridement of infected and necrotizing tissue. All necrotic skin, subcutaneous tissue, fascia and nonviable muscle were removed, the excised tissue was sent for culture and sensitivity in microbiology laboratory. All the viable skin and soft tissues were saved to aid later closure. Result: the survival rate was 86.5% in patients who underwent surgical debridement in early stage of disease as compared to 61.5% mortality in patients who presented late. Septicemic shock and multiple organ failure was less in patients who presented at early stage of disease. Early and adequate nutritional support along with prompt recognition and treatment reduces the development of multiple organ failure and improves the outcome. Conclusion:Mortality rate is decreased in those patients who are treated in early cause of disease by means of surgical and medical approach. The mortality rate is directly proportional to involved body surface area in patients of Necrotizing soft tissue lesion. Site of lesion and extent of lesion influences the mortality.