Objective: To enhance our understanding of reward stimuli in anorexia nervosa (AN) and to provide a basis for future research on reward processes, disorder specific reward stimuli as well as primary and secondary reinforcers were investigated.Method: We developed a set of pictures with "disorder specific reward" stimuli, with the six subcategories "sport," "losing weight," "healthy food," "discipline," "thin bodies," "appreciation of others," and evaluated reward ratings of these "disorder specific reward" stimuli as well as "erotic," "high caloric," and "neutral" stimuli in 25 patients with AN and 25 participants in the comparison group (CG).Results: We found a significant main effect for picture category and a significant interaction. The reward ratings were higher in patients with AN compared with CG for the "disorder specific reward" stimuli. In the reward subcategories, patients with AN had higher reward ratings compared with CG in all categories except of healthy food. The "disorder specific reward" stimuli of the categories "sport," "losing weight," and "healthy food" showed higher reward ratings compared with the categories "discipline," "thin bodies," and "appreciation of others" in patients with AN.

A 55-year-old Caucasian man with relapsing-remitting multiple sclerosis (RRMS) presented to hospital with headache, neck pain, nausea and chills. Symptoms started 3 hours prior to his presentation. Clinical examination showed meningism. MS was diagnosed in 2018 and was currently treated with dimethyl fumarate (DMF) (480 mg/day) for the last 9 months (4/20-1/21). Recommended white blood cell controls had not been realized in the last 6 months by the outpatient physicians. Previous MS therapy was 300 mg ocrelizumab in March 2018, after one infusion this therapy was stopped on patients' request. His medical history included type 2 diabetes mellitus (HbA1c 6.4%; normal value: 4.8-6.0), hypertension and coronary artery disease.Upon admission, blood count showed a normal white cell count (9480/µl) but marked lymphopenia (240/µl). C-reactive protein was 18.40 mg/l (normal value < 5 mg/l), procalcitonin was 4.68 ng/ml (normal value 0.5 ng/ml). U-Status showed a urinary tract infection (UTI), blood

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