Age and gender differences in preferences for same-and other-gender peers as partners for working on a school project and casual interactions at home were investigated. Participants were 82 students (19 sixth-grade preadolescents; 29 eighth-grade adolescents; 34 tenth-and eleventh-grade older adolescents). Same-gender preferences were assessed via peer nominations and ratings of expected enjoyment of interacting with same-and other-gender peers. Preferences varied by context: individuals expected to enjoy same-gender peers more than other-gender peers when working on a project at school but not when interacting casually at home. Greater expected enjoyment of same-gender peers over other-gender peers was most pronounced for preadolescent boys and girls, and least pronounced for older adolescent males. Nominations of same-gender peers for home and school activities decreased with age. Results are interpreted in light of a social-contextual approach to gender segregation.