Background
There is evidence that metabolic syndrome (MS), as a cluster of acute coronary syndrome (ACS) risk factors, is associated with increased left ventricle mass index (LVMI). According to the 2009 IDF criteria of MS diagnosis, elevated waist circumference (≥94 cm in M, ≥80 cm in F), as a determinant of abdominal obesity (AO), is not an obligatory component of MS. Little is known about the relation of abdominal obesity to LVMI in pts with ACS.
Purpose
The aim of this study was to evaluate the relationship between abdominal obesity and LVMI, determined as LVM/H2,7, in patients with MS hospitalized due to ACS.
Methods
444 consecutive pts were enrolled based on ACS diagnosis. The pts were divided into two groups depending on MS diagnosis: group A – 310 pts with MS and AO (205 M, mean age 63.3 ± 10.5 yrs), group B - 134 pts without MS (101 M, mean age 61,4 ± 12.7 yrs). The group A was divided to two subgroups depending on AO diagnosis: group A1 - 288 pts with MS and AO (185 M, mean age 63.4 ± 10.2 yrs and group A2 - 22 pts with MS without AO (19 M, mean age 62,6 ± 12.7 yrs). In all enrolled pts hypertension was diagnosed.
Results
A significant difference was found between group A and B with the respect to LVMI (68.4 ± 25.9 vs. 58.3 ± 16.5, p < 0.05). In the group B, a significant association was found between LVMI and waist circumference (r = 0.39, p < 0.05), weight (r = 0.22, p = 0.012), as well as BMI (r = 0.35, p < 0.05). In group A, LVMI was significantly correlated only with weight (r = 0.24, p < 0.05). No significant differences were found between pts with AO and without AO with respect to LVMI (68.9 ± 26.2 vs. 61.4 ± 20.9, p = 0.187).
Conclusion
1. In individuals without MS hospitalized due to acute coronary syndrome significant positive correlation was found between LVMI and waist circumference, weight as well as BMI. 2. There is significant difference between pts with MS and without MS with the respect to LVMI. 3. No significant differences were found in LVMI between pts with AO and without AO.
