A direct scattering optical coherence tomography forward model was
developed to simulate A-scans for both idealized and real light
sources on an arbitrary given sample structure. Previous models
neglected absorption, scattering, and multiple reflections at
interfacial layers, and so two extended models were developed to
investigate the impact of these processes. The first model uses the
Beer–Lambert law to incorporate both absorption and scattering optical
processes, and the second model uses a recursive form to model
multiple reflections. These models were tested on a structure
representative of a multilayered skin sample. The results show that
the absorption and scattering processes have significant impact on the
height of the peaks in the simulated A-scans. Conversely, the
incorporation of multiple reflections has very little impact on the
height of these peaks. Neither of the above processes has any impact
on the locations of the A-scan peaks, which are associated with the
sample interfaces between layers.
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