Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous
disease. It results in linear deposition of autoantibodies (immunoglobulin A)
against antigens in the basal membrane zone, leading to subepidermal cleavage.
Additional depositions of immunoglobulin G and complement-3 might occur. It is
still debated whether concomitant findings of immunoglobulins A and G should be
considered a subtype of this dermatosis or a new entity. Further studies are
needed to recognize this clinical variant.
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