Purpose We compare anterior segment characteristics of Filipino- versus Chinese- and Caucasian-Americans to describe the differences in risk factors among each ethnic group. Methods A cross-sectional study was conducted among Filipino, Chinese, and Caucasian subjects without glaucoma who underwent a standardized set of ocular examinations and anterior segment optical coherence tomography (Visante ASOCT) imaging. Zhongshan Angle Assessment Program (ZAAP) 4 was used for ASOCT image analysis. The following quantitative parameters wereobtained from ZAAP: (1) angle opening distance (AOD500, AOD750), angle recess area at 750 μm (ARA), and trabecular-iris space area at 500 and 750 μm (TISA500, TISA750); (2) iris parameters, including iris thickness at 750 μm from the scleral spur (IT750), iris area (IArea), iris curvature or convexity (ICurv), and pupil diameter; 3) anterior chamber parameters; and (4) lens vault. Results The Filipino (122 eyes), Chinese (121 eyes), and Caucasian (111 eyes) subject groups were similar in terms of demographic and clinical characteristics. We reported pairwise comparisons of Filipino parameter values to Chinese or Caucasian values, represented as B-coefficients and P values. In multivariate analysis, Filipinos had narrower angles than Caucasians (AOD750, TISA 500, TISA 750, ARA, P < 0.001). Filipinos had thicker and more convex irises than Caucasians (IT750, IT 2000, ICurv P < 0.003). Angle and iris parameters were similar overall for Filipino and Chinese. Conclusions Filipinos appear to have more convex and thicker irises, smaller lens vault and narrower angles compared to Caucasians. Filipino eyes closely resembled Chinese eyes with similar iris and angle parameters. Translational Relevance The anatomic angle parameters of Filipinos may contribute to angle closure risk among this population, thus ASOCT and thorough angle analysis is recommended in this population.
Précis: Corneal hysteresis (CH) measurements are relatively stable during routine follow up of glaucoma patients over an intermediate time frame. Cataract surgery does not change the CH significantly after an average follow up of 6 months. Purpose:The aim was to assess the repeatability of CH measurements in glaucoma patients over time, during routine follow up and after cataract surgery.Materials and Methods: Retrospective analysis of patients records in a glaucoma clinic where routine measurements by the Ocular Response Analyzer were done. Patients with at least 2 CH measurements were included. Repeatability was assessed using the intraclass correlation coefficient (ICC).Results: A total of 164 eyes (87 patients) were included. Twentyeight of them had measurements before and after cataract surgery with mean follow up time of 29.64 ± 9.63 weeks. There was no evidence for a difference in CH between the before and after cataract surgery measurements (ICC = 0.79, 95% confidence interval: 0.60-0.89). In the remaining 136 eyes, without any surgical treatment between measurements, there was moderate agreement among the repeated CH measurements (ICC = 0.64, 95% confidence interval: 0.61-0.82) with mean time of 32.06 ± 25.32 weeks between first and last measurement.Conclusion: CH measurements in glaucoma patients were repeatable over a 6-month period during routine follow up or following cataract surgery. These findings suggest that the intraocular pressure reduction following cataract surgery is unlikely to be because of a change in this biomechanical property.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.