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Iron clearance from the skin was measured in 10 normal subjects and two patients with iron‐deficiency anaemia. Some of the iron injected into the skin is probably bound to transferrin in the interstitial fluid whilst the remainder is rapidly removed into the blood stream. Approximately two‐thirds of the bound iron is cleared with a half‐life of about 1 day, the remainder disappearing slowly with a half‐life of about 60 days.

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Of 73 patients treated for ovarian carcinoma at the University of Nebraska Medical Center between 1976 and 1982, 37 underwent a second operative procedure following initial surgery. A total of 14 had a second look following complete clinical response, 11 had intestinal diversion, and 12 underwent other procedures. Second-look surgery proved useful in evaluating patients in clinical remission and directing subsequent management. The majority of patients whose operations were for persistent or recurrent disease had short survival. However, such surgery helps occasional patients and should be considered when circumstances warrant.-.KEY WOHIIS: ovarian carcinoma, second-look operations, palliative operations, ovarian adenocarcinoma