Sodium dipyrone undergoes the biotransformation effect, in order to achieve activation in higher potency, producing metabolites and consequently improving the absorption and action of this drug. It presents analgesic and antipyretic action in vivo, designed to act with antiplasmóticas and anti -inflammatory properties, being very used for simple pains to the chronic pains. The study analyzed the content of the concentration of dipyrone tablets marketed in drugstores in the city of Vitória da Conquista -BA, in which it used the UV absorption spectrophotometry method in 500 mg samples of reference brands, generic and similar. The results obtained in the analysis had an average concentration content for generic drugs 95.93%, similar 91.17% and reference 92.92%. According to the Brazilian Pharmacopoeia the values must be between 95% and 105% to be able to attend pharmacotherapy. Therefore, the drug of the generic class was fit for consumption, since its concentration meets the standards of the Brazilian Pharmacopoeia.
The psychological factors encompass a vast consumption of prolonged and continuous use drugs, whose purpose is to soften the clinical manifestations that comorbidities present. The concomitant use of more than five drugs may lead to a reduction in adherence to treatment and therefore the unsatisfactory drug effectiveness. The present article aims to evaluate individuals aged 45 to 60 years with some of these psychological factors: anxiety, depression and / or stress, as well as adherence to drug therapy. This is a descriptive, cross-sectional and quantitative approach, performed in the city of Vitória da Conquista, Bahia, Brazil. For obtaining the results, it was adopted the socioeconomic questionnaires, BAI, BDI, ISSL and Abuel. The sample was composed by 389 individuals of both genders. Individuals with anxiety reported a greater intake of natural drugs for pain, sleeping, and depression. Individuals with depression reported a higher intake of the drugs described above, plus anxiety. Individuals with stress reported a greater intake of the same drugs than those ones described by anxiety, plus the drug for anxiety.
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