study focuses on synthesis of benzimidazole derivatives by numerous homogeneous catalysts related from s-block, pblock, transition metal, inner transition metal and environmentally benign synthetic approaches, via heterogeneous catalyst in metal-free conditions. Benzimidazole has several applications in pharmaceuticals, agrochemicals and fine chemicals. Its scaffolds are omnipresent in several bioactive natural products and pharmaceutically important compounds. This review highlights synthetic approaches and studies of benzimidazole reported from the year 2020 onwards.
Mucormycosis emerged as major post COVID complication in India. Its management involves Amphotericin B and surgical debridement. Anaesthesia becomes challenging in such patients due to compromised patients, extensive surgery and side effects of Amphotericin B. We present the successful management of a rhino-cerebral mucormycosis patient with lidocaine infusion.
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