In this paper, we propose an analog network coding scheme with differential modulation (ANC-DM) using amplify-and-forward protocol for bidirectional relay networks when neither the source nodes nor the relay knows the channel state information (CSI). The performance of the proposed ANC-DM scheme is analyzed and a simple asymptotic bit error rate (BER) expression is derived.The analytical results are verified through simulations. It is shown that the BER performance of the proposed differential scheme is about 3 dB away from that of the coherent detection scheme.To improve the system performance, the optimum power allocation between the sources and the relay is determined based on the simplified BER. Simulation results indicate that the proposed differential scheme with optimum power allocation yields 1-2 dB performance improvement over an equal power allocation scheme.

Recently, cardiovascular disease (CVD) has become one of the leading death causes worldwide, and it contributes to 41% of all deaths each year in China. This disease incurs a cost of more than 400 billion US dollars in China on the healthcare expenditures and lost productivity during the past ten years. It has been shown that the CVD can be effectively prevented by an interdisciplinary approach that leverages the technology development in both IT and electrocardiogram (ECG) fields. In this paper, we present WE-CARE , an intelligent telecardiology system using mobile 7-lead ECG devices. Because of its improved mobility result from wearable and mobile ECG devices, the WE-CARE system has a wider variety of applications than existing resting ECG systems that reside in hospitals. Meanwhile, it meets the requirement of dynamic ECG systems for mobile users in terms of the detection accuracy and latency. We carried out clinical trials by deploying the WE-CARE systems at Peking University Hospital. The clinical results clearly showed that our solution achieves a high detection rate of over 95% against common types of anomalies in ECG, while it only incurs a small detection latency around one second, both of which meet the criteria of real-time medical diagnosis. As demonstrated by the clinical results, the WE-CARE system is a useful and efficient mHealth (mobile health) tool for the cardiovascular disease diagnosis and treatment in medical platforms.

The paper describes a convenient and facile methodology for the regioselective synthesis of fused oxazepinone scaffolds. This process is an efficient construction of the oxazepinone scaffold by a one-pot coupling/Smiles rearrangement/cyclization approach. This transition metal-free process has potential applications in the synthesis of biologically and medicinally relevant compounds.

Pyrroloquinoxalines have proved to be a very attractive scaffold for medicinal chemist in the recent past. These compounds were extensively studied as bioactive compounds and many of them are known to be biologically and medicinally useful molecules, such as anti-HIV agents, antimalarial agents, antagonist agents, anticancer agents, and PARP-1 inhibitors. Additionally, pyrroloquinoxalines are also important intermediates for the construction of 5-HT3 receptor agonists. In this review the developments in biological activities and synthetic methodologies of pyrroloquinoxalines are discussed.

A copper-catalyzed one-pot process for the construction of benzo [4,5]imidazo[1,2-a]quinoxalines under air is described. Aryl chlorides, aryl bromides, and aryl iodides can be applied to the synthesis of these compounds.