Multispectral imaging techniques improve the accuracy of spectral reconstruction as well as color measurement in imagebased data capture systems compared to the conventional RGB cameras. On the other hand, high dynamic range imaging provides recording a higher range of scene radiance values when the dynamic range of the camera does not cover values between the minimum and maximum radiances of the scene. In high dynamic range imaging, camera response function plays a crucial role in the irradiance map reconstruction. It could be either absolutely measured by laboratory equipment or relatively estimated through a set of images with different exposure times. In this work, camera response function assessment has been addressed for a filter wheel multispectral camera. Both measurement and estimation methods are investigated through experiments and results are compared to the ground truth data. The results showed high dynamic range imaging with measured absolute camera response function has two benefits: it measures radiance in the same scale and physical units, and outperformed in terms of the precision of reflectance measurement.