Background: The ongoing coronavirus disease-19 (COVID-19) pandemic (caused by an infection with severe acute respiratory syndrome (SARS)-coronavirus (CoV-2) has put a burden on the medical community and society at large. Efforts to reduce the disease burden and mortality over the course of the pandemic have focused on research to rapidly determine age-stratified seroepidemiologic surveys, a centralized research program to fast-track the most promising rapid diagnostics and serologic assays, and the testing of potential anti-viral agents, immunologic therapies, and vaccine candidates. Despite the lack of official recognition for the role of nutrition in the fight against COVID-19 infection, multiple groups proposed zinc supplementation as an adjuvant for the management of participants.Method: In an ambulatory, interventional, prospective, single-blind study, we evaluated the effectiveness of zinc supplementation in the prevention and mitigation of COVID-19 in two similar participant groups. In Clinic A (n = 104) participants were randomized to receive 10 mg, 25 mg, or 50 mg zinc picolinate daily, and Clinic B control participants paired according to their demographics and clinical parameters (n = 96). All participants were compared based on demographics, clinical comorbidities, blood counts, renal functions, vitamin D levels, and their development of symptomatic COVID-19 infection.Results: Symptomatic COVID-19 infection was significantly higher among the control group participants (N = 9, 10.4%) than the treatment participants (N = 2, 1.9%), p = 0.015. The unadjusted odds ratio indicates that symptomatic COVID-19 infection was 5.93 [95% CI: 1.51, 39.26] higher in the control group, p < 0.01. Controlling for co-morbidities, individuals in the control group were 7.38 (95% CI: 1.80, 50.28) times more likely to develop symptomatic COVID-19 infection as compared with individuals in the treatment group (p < 0.01). For every-one unit increase in the number of co-morbidities, the likelihood of developing symptomatic COVID-19 infection increased 1.57 (95% CI: 1.16, 2.19) (p = 0.01).Discussion: The findings from our study suggest that zinc supplementation in all three doses (10, 25, and 50 mg) may be an effective prophylaxis of symptomatic COVID-19 and may mitigate the severity of COVID-19 infection.Conclusion: Zinc is a relatively inexpensive mineral nutrient that is an effective prophylactic agent to prevent and mitigate the potentially deadly symptomatic SARS-CoV-2 infection. As the COVID-19 pandemic continues with a lag in vaccinations in some regions and the continued emergence of dangerously infectious variants of SARS-CoV-2, it is important to replicate our data in other populations and locations and to engage public health and nutrition services on the emergent need to use zinc supplantation or fortification of staple foods in the prevention and mitigation of COVID-19 infection severity.

Enteral nutritional support is an important and effective means of providing needed nutrients to patients. Four levels of support can be defined. Most patients are able to eat the diet prescribed for them (level 1), but some require forced nutritional support given by nasogastric (level 2) or nasoenteral (level 3) feeding tubes or by gastroenterostomy (level 4). Selection of the appropriate tube from among the many commercially available types with different features is important to minimize the risk of medical complications. How the tube is placed depends on whether the patient can or will cooperate. Proper positioning of the tube can be checked without an x-ray film by determining if four criteria have been met in a specified order.

A field study was conducted to evaluate the nutritional status of newly arrived Cuban refugees. The protocol consisted of socioeconomic, clinical, anthropometric, laboratory, and dietary investigations. A total of 138 refugees was studied at Opa Locka, Fl. The results revealed that 25% of children suffered from malnutrition mostly of the first degree. Second degree malnutrition was rare and cases of third degree malnutrition or infantile kwashiorkor were not found. Obesity was found in 17% of women. Of adults 25% had significantly low adipose tissue stores. Lean body mass was estimated by anthropometry and found to be adequate in 88% of adults. Fifteen percent of adults and 12% of children had anemia. The foods most frequently consumed by the refugees in Cuba were bread, eggs, rice, and garbanzo (chick peas). Fruits and vegetables were not consumed in Cuba daily by the majority of the refugees.

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