The issues of risk management that can arise systematically in the economic and financial activities of the organization are considered. The understanding of the essence and content of risks, the process of risk management is presented. The types of risks, methods of risk assessment and risk management are considered. For students studying in the areas of "Economics" and "Management", as well as engineering and technology directions of universities that study the disciplines of the economic and organizational cycle; For graduate students, students of business schools and the system of advanced training and retraining of personnel. It can be useful for teachers of universities, employees of research and consulting firms, business structures, managers and specialists of enterprises.

The article deals with current issues of management development in the world and in Russia. The analysis of the development of management in different periods of time and its current status is given. The factors and assumptions to develop a new concept of management, defined its most important features and conditions of sale are considered.

At present remains urgent aid to oncologic patient in IV - oh the stage of disease. In proportion to the advance of the contemporary procedures of treatment oncologic science enlarges the possibilities of an improvement in the quality of the life of the named contingent of patients. Because of the new technologies in oncology it is possible to conduct tsitoreduktivnye, palliative and maloinvazivnye operations and manipulations, which make it possible to increase the quality of the life of this heavy contingent of patients. As a result surgical treatment and maloinvazivnykh opretsiy and manipulations in oncologic sick IV-oh stage appears surgical injury, oxidizing stress, disturbance of homeostasis and oppression of immunity, which leads to an even larger immunodeficiency in the named contingent of patients. The oppression of the unspecific resistibility of organ-ism as a result occurs. The application of adaptogena of the elixir of Altai (Vitavis) in combination with the ionic- activated aqueous means makes it possible to level and to reduce on no oxidizing stress of the organism of oncologic patients in the last stage of disease. After the application of treatment of the named technology the unspecific resistibility of organism rises, immune-scarcity considerably decreases. Powerful antioxidant – the ionnoaktivirovannoe aqueous means strengthens the action of immunnomodulyatora of adoptogena of the elixir of Altai (Vitavis), which leads to the decrease of postoperative infectious complications in oncologic sick IV-oh of the stage of disease, reduces postoperative period, improves the quality of life and enlarges indications to conducting even of complex operations, maloinvazivnykh operations and manipulations.

эликсир Алтайский («Витавис»), ионно-активированные водные средства, метастатические переломы позвоночника.

In recent years there has been a marked increase in the number of patients with primary and metastatic tumors of the musculoskeletal system. Skeletal system is one of the most affected in various cancer diseases, such as breast, prostate, kidney, thyroid, lung cancer, gastro-intestinal tract. The authors use the individual metal-polymer express-endoprosthesis for replacement of bone defects in primary and secondary tumors of the musculoskeletal system and spine. The purpose and the objectives of this study were to present the possibilities of proposed surgical technique and to increase its effectiveness by the use of the new immunodiagnostic methods. The essence of immunodiagnostics was assessment the state of natural immunity to the definition of autoantibody levels only in the affected organs, as well as immune correction in the early postoperative period using immunoglobulins, fast adaptogens, immunomodulators "Vitavis" and powerful antioxidant neutral Anolyte produced at the facility Stela NPO "Screen" of the Medical and Technical Academy. Use of the fast adaptogens, immunomodulators, neutral Anolyte, immunoglobulins allows to optimize postoperative dynamics of biochemical and immune parameters, to reduce the risk of complications and to accelerate wound healing, to speed up the "engraftment" implants, to reduce the postoperative period. A new approach to the evaluation of the immune status at the level of oncological diseases of autoimmunity allows to identify the affected tumor process bodies (lesions, microlesions, metastases, hidden metastases), to detect the presence of systemic activation or suppression of the immune system, which is the justification for the use of immunosuppressive or immunostimulatory therapy. Identifying systemic immunosuppression by humoral type allows to use new methods of immunotherapy of oncological diseases - Ig-therapy, as well as to select individual regimens according to the degree of immunosuppression.