Purpose Increased prevalence of myopia is a major public health challenge worldwide, including in Africa. While previous studies have shown an increasing prevalence in Africa, there is no collective review of evidence on the magnitude of myopia in African school children. Hence, this study reviews the evidence and provides a meta-analysis of the prevalence of myopia in African school children. Methods This review was conducted using the 2020 Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. Five computerized bibliographic databases, PUBMED, Scopus, Web of Science, ProQuest, and Africa Index Medicus were searched for published studies on the prevalence of myopia in Africa from 1 January 2000 to 18 August 2021. Studies were assessed for methodological quality. Data were gathered by gender, age and refraction technique and standardized to the definition of myopia as refractive error ≥ 0.50 diopter. A meta-analysis was conducted to estimate the prevalence. Significant heterogeneity was detected among the various studies (I2 >50%), hence a random effect model was used, and sensitivity analysis was performed to examine the effects of outliers. Results We included data from 24 quality assessed studies, covering 36,395 African children. The overall crude prevalence of myopia over the last two decades is 4.7% (95% CI, 3.9–5.7) in African children. Although the prevalence of myopia was slightly higher in females (5.3%, 95%CI: 4.1, 6.5) than in males (3.7%, 95% CI, 2.6–4.7; p = 0.297) and higher in older [12–18 years 5.1% (95% CI, 3.8–6.3) than younger children (aged 5–11 years, 3.4%, 95% CI, 2.5–4.4; p = 0.091), the differences were not significant. There was a significantly lower prevalence of myopia with cycloplegic compared with non-cycloplegic refraction [4.2%, 95%CI: 3.3, 5.1 versus 6.4%, 95%CI: 4.4, 8.4; p = 0.046]. Conclusions Our results showed that myopia affects about one in twenty African schoolchildren, and it is overestimated in non-cycloplegic refraction. Clinical interventions to reduce the prevalence of myopia in the region should target females, and school children who are aged 12–18 years.
Malaria is caused by the parasite plasmodium which can be spread to humans through the bite of an infected mosquito. Of the five types of plasmodium (P. Falciparium, P.Ovale, P. Malaria, P. Vivax and P. Knowlesi), the plasmodium falciparium is the deadliest and affects the lives of almost 40 per cent of the world’s population with pregnant women and children under-five years of age being the most affected. This mini-review involved the collation of findings from recent studies in regards to the prevalence of malaria infection among pregnant women and infants. A systematic analysis of recent literature on the prevalence of malaria in pregnancy from many authors was carried out and the facts synthesized to make an easy read. From the analysis of literature, Ten Thousand women and 200,000 babies were reported to be dying annually from complications of malaria in pregnancy which recorded a prevalence of 85 per cent in sub-Saharan Africa. More so, Fifty per cent of pregnant women were discovered to be carrying plasmodium falciparium in their placenta without even experiencing malaria signs/ symptoms, and this development was reported to have been responsible for Twenty per cent of stillbirths and 11 per cent of all maternal deaths. Malaria infection is considered a major threat to the lives and well-being of pregnant women and infants. Therefore, stakeholders should ensure that every clinical diagnosis of malaria in pregnancy is confirmed with a laboratory plasmodium falciparium-based diagnosis before the administration of antimalarial drugs. Furthermore there should be a stepping –up on the distribution of insecticide treated nets alongside enlightenment of pregnant women on ways of preventing mosquito bite. Instituting the aforementioned approaches is key to improving the health- seeking behaviour of pregnant women in particular and the wider population in general thus enabling them to stay malaria free throughout the period of pregnancy and infancy.
Background: Visual impairment among school children is relatively common and research provides evidence for integration of comprehensive eye care into school health programmes.Aim: To determine the prevalence and determinants of visual impairment in school-aged children in Southern Nigeria.Setting: School aged children from 10 public and private-owned schools in Cross River State, Southern Nigeria. Methods:This cross-sectional analytic study used a multistage random sampling technique to select 2418 school children aged 6-17 years. Comprehensive eye examinations were performed on the study. The logistic regression analysis with 95% confidence interval (CI) was used to test hypotheses.Results: Of the 2418 school children selected, 2110 (87%) were assessed. The prevalence 'of uncorrected, presenting and best corrected visual acuity of 0.3 (20/40) or worse in the better eye' was 7.3%, 7.2% and 0.19%, respectively. Errors of refraction were the cause of the impairment in 198 (70.7%; 63.5-76.0) eyes with reduced vision, followed by glaucoma suspects 38 (19.2%; 13.8-24.8), amblyopia (3.0%; 1.1-6.4) and corneal opacity 3 (1.5%; 0.3-4.3). The major and independent predictors of visual impairment were age (adjusted odds ratio [AOR] 1.97, 95% 1.45-2.67), high socio-economic status (adjusted odds ratio [AOR] 1.68, 95% 1.36-2.09) and female gender (AOR 1.35, 95% 1.00-1.88). Conclusion:The common causes of visual impairment in school-aged children are avoidable, and are mostly because of uncorrected refractive error, which could reflect inadequate refractive error services in the area.
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