Background: Diabetes Mellitus (DM) is a metabolic disorder precipitating micro-vascular, macrovascular complications and peripheral vascular disease. Less has been known about the after effect of diabetes on lungs. So this work was carried out to know the effect of diabetes mellitus on pulmonary functions. Objective: To find out the effect of diabetes mellitus on pulmonary functions in type 2 DM Material and method: A case-control study was conducted on 30 type 2 DM patients and age sex matched 30 controls after screening both the groups for smoking and acute/chronic pulmonary disease. All subjects underwent screening with detailed history, anthropometry and spirometry at Department of Physiology, SMS medical college, Jaipur. Significance of difference of pulmonary parameters in both the groups was inferred with unpaired't' Test. Result: Diabetic patients showed highly significant (P<0.001) reduction in almost all the pulmonary parameters. The reduction in pulmonary parameters was not associated with severity and duration of disease. Conclusion: Diabetic patients showed impaired lung function independent of smoking. Although it was not associated with severity but duration of DM affect FVC and FEV 1 .
Introduction:
Male pattern alopecia (MPA) is a common disorder hugely impacting the quality of life of affected individuals. The meager number of options available for treatment has their own limitations. Novel therapies are continuously being researched for.
Materials and Methods:
The present study included thirty male patients with Hamilton Grade II to Grade V. All patients received four sequential treatments with microneedling (MN) on one half of the scalp and platelet-rich plasma (PRP) with MN (MN + PRP) on the other half for 4 months. Three months following the last session, evaluation was done from the vertex and temporal sites in both the groups by dermoscopic microphotographs by a blinded evaluator. In addition, the patients were asked about their satisfaction score on the basis of treatment outcome.
Results:
Overall hair thickness showed significant increase in both MN and MN + PRP group. Furthermore, the increase in thickness was almost double in the MN group as compared to MN + PRP group (0.006 and 0.003 mm, respectively). Overall hair density also increased significantly in both the study groups but more in MN + PRP group (14.6 hair/cm
2
) than the MN group (10.8 hair/cm
2
). However, the difference between the results of both the groups was not statistically significant.
Conclusion:
To the best of our knowledge, this is the first split scalp study for MPA. We conclude that MN and PRP are both effective in treatment of androgenetic alopecia and improve the hair parameters and patient satisfaction. However, no additional effect of PRP over MN was observed. Both these therapies are safe and well tolerated without any major side effects. Limitations of our study were small sample size and lack of long-term follow-up.
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