National Health and Wellness Surveys (NHWS), a cross-sectional, Internet-based survey. The NHWS includes a sample of urban (Tier I and II cities) adults (≥ 18 years) which included items on vaccination history and high-risk status defined by the World Health Organization(WHO). Vaccination rates and characteristics of vaccinees were reported descriptively. Logistic regressions were conducted to predict vaccination behavior from sociodemographics and riskrelated variables. Results: Only 13.69% of adults in urban China reported being vaccinated for influenza in 2013. Among patients in high-risk groups (coronary heart disease [CHD], chronic lung conditions etc.), vaccination rates were low for most groups, ranging from 5.7% (≥ 65 years) to 57.69% (chronic neurological conditions). The most common reason for non-vaccination was belief that it was not needed (17.8%); other common reasons for non-vaccination included believing that the vaccine is not effective (12.9%) and not getting a vaccine before (9%). Respondents who were vaccinated were less likely to be older (OR= 0.982), currently married (OR= 0.792) and university educated (OR= 0.748), and more likely to be female (OR= 1.403), a current smoker (OR= 1.387) exercised more on average (OR= 1.023), consumed alcohol regularly (OR= 2.299), feared needles more (OR= 1.111), and had higher incomes (RMB6,000 or more) (OR= 1.62) compared with those not vaccinated. The strongest predictors of vaccination were having CHD (OR= 2.161), chronic lung (OR= 2.069), chronic liver (OR= 1.891), chronic metabolic condition (OR= 1.835), or chronic renal conditions (OR= 1.758)(all p< .05). cOnclusiOns: Overall vaccination rates were low in China. Most WHO-recommended vaccination groups had rates less than 20% and a large gap remains between these recommendations and vaccination behavior. In 2011, the influenza vaccination rates among adults in the United States were 36.2%, almost three times the vaccination rate in urban China. PIN11

OBJECTIVES: Irritable bowel syndrome (IBS) is a relapsing, chronic functional gastrointestinal disorder leading to long-term disturbances on health-related quality of life (HRQoL). Various functional and QoL measures have been developed to evaluate IBS outcomes, but none of the preference-based QoL measure has been applied and validated on Taiwanese people. This study aimed to explore the feasibility of applying preference-based HRQoL measures to IBS patients in Taiwan. METHODS: This prospective study was conducted from July to December 2010 at gastroenterology clinics in a regional hospital in southern Taiwan. IBS outpatients diagnosed by Rome III criteria were invited into participate semi-structure interview survey by using EuroQol (EQ-5D) questionnaire, 100-mm visual analogue scale (EQ-5D VAS) and standard gamble (SG) method. The EQ-5D assessment was transformed into EQ-5D index using Japanese preference weight. Multiple regression was used to assess factors associated with utilities, e.g. demographic, socioeconomic status and disease severity. RESULTS: Of all, 29 participants (mean age 45.8Ϯ16.5 years; 62.1% female) completed QoL survey, except for one rejected SG survey for disagreeing with SG hypothesis. Participants' IBS subtypes include constipation (nϭ11; 37.9%), diarrhea (nϭ16; 55.2%) and unsubtyped IBS (nϭ2; 6.9%); and 12 (41.4%) participants were newly diagnosed IBS and 12 had over two-year disease history. Participants had no problem in EQ-5D survey, some expressed difficulties in dimensions of pain/discomfort and anxiety/depression. Mean utility derived from SG (0.85Ϯ0.16), EQ-5D index (0.79Ϯ0.15) and EQ-5D VAS (0.59Ϯ0.17) were significantly different (pϽ0.05). SG utility was significantly associated with unsubtyped IBS and whether the IBS was newly diagnosed (pϽ0.05). CONCLUSIONS: IBS is well-tolerated but causing problem in anxiety/depression and pain/discomfort in QoL survey. Mean utility of SG is higher than results derived from EQ-5D and EQ VAS, and this finding matches previous literature. Further validate the utility measures in more IBS patients with various subtypes and severity is needed.

S105OBJECTIVES: Community pharmacy is a major link in the asthma therapy chain. However, community pharmacists have insufficient knowledge about asthma and asthma medications for counselling patients effectively in Vietnam. The study aimed to investigate improvement in knowledge and practice of community pharmacists in asthma counselling after attending a short training course. METHODS: 300 pharmacists consented to participate in a study using simulated patients. A knowledge questionnaire about asthma medications and a standardized inhaler checklist were designed to test before and after training. Pharmacists were invited to attend a short training course (3h) focused on counselling asthma patients (asthma control, distinguish relievers and controllers, side effects, medication adherence, inhaler technique teaching). After the training, 10 simulated patients trained with a standardized asthma case were sent to the community pharmacy to test the pharmacist's knowledge and practice. RESULTS: After the training, number of correct answer and score of asthma knowledge of pharmacists increased remarkably (p< 0.001). While there was no pharmacist performed correctly both metered-dose inhaler (MDI) and dry powder inhaler (DPI) in pre-training, > 50% performed correctly in post-training (p< 0.001). Regarding tested by simulated patients, knowledge and practice of pharmacists in the training group improved significantly. 94.3% of pharmacists in training group could distinguish relievers and controllers compared with under 50% in no-training group (p< 0.001). Percentage of pharmacists counselling correctly about controller adherence in training group was statistically higher than no-training group (91.8% vs 63.6%). Pharmacists attended training also performed better in counselling asthma patients about side effects of asthma medications (p< 0.001). When teaching patients in pharmacy, inhaler technique score of training group was significantly higher than the no-training group (6.1 vs 4.3, p< 0.001). CONCLUSIONS: A short training course was effective in providing community pharmacists with necessary knowledge about asthma and medications to improve quality of counselling asthma patients in community pharmacy

culate TTR, and TTR Ͻ55% was defined as "lower TTR". CHADS 2 Ն2 was defined as "higher CHADS 2 ". Logistic regression analyses were conducted to determine the association between comorbidities and TTR. RESULTS: We identified 23,425 patients. The mean (ϮSD) age was 74.8Ϯ9.7 years, with 84.8% Ն65 years. The most common comorbidities were hypertension (41.7%), diabetes (24.1%), HF (11.7%), and stroke (11.1%). The mean (ϮSD) TTR was 67.3Ϯ14.4; 18.7% of patients had "lower TTR". In multivariable analyses, using age, gender, hypertension, diabetes, stroke, and region as covariates, HF was associated with "lower TTR" [adjusted OR (95%CI) ϭ 1.

No abstract