Background: Coronavirus diseases 2019 (COVID-19) has become global pandemic. During the COVID-19 pandemics, caused by SARS-CoV-2, overall, children younger than 18 years are thought to account for only 1% to 2% of detected cases worldwide. COVID-19 has been found less frequent in children and studies on pediatric COVID-19 have also been less reported, especially from Bangladesh. To evaluate the clinical profile of RT-PCR- positive paediatric patients with COVID 19 in Chattogram region. Materials and methods: This cross-sectional study was conducted in OPD, Department of Paediatrics, Chittagong Medical Colllege Hospital (CMCH) Chattogram. All postCOVID paediatric patients reported as RT-PCR positive by Microbiology department of CMCH were enrolled in the study. The study was carried out from 1/8/21 to 31/01/22. According to inclusion/exclusion criteria 96 RT-PCR positive COVID-19 paediatric patients were taken as sample by convenient sampling for this study. The diagnosis of COVID 19 infection was confirmed by RTPCR report of nasopharyngeal or oro-pharyngeal swab. Patients, guardians were contacted over telephone to attend paediatric OPD of CMCH for clinical information & laboratory findings.   Results: Among them 96 children, 68.8% were in >5 years, 18.8% were in 1-5 years, and 12.4% were in the <1 year age group; 55.2% were female and 48.8% were male. About 66 (80%) patients had history of contact with suspected or confirmed COVID-19 patient. Total 21 patients got hospitalized. Mean ± SD of time from symptom onset to hospital admission was 4.76 ± 1.998 days. Duration of hospital stay was ranged from 4-14 days. Mean ± SD duration of hospital stay was 6.1 ± 2.385 days. Maximum (97.9%) patients had fever, 77.1% patients had cough and 29.2% patients had vomiting.  Majority (82.3%) of the patients had no co-morbidities. Mean ± SD Hb% (g/dl) was 12.04 ± 1.817 g/dl with range: 7-16 g/dl; median (IQR) WBC (/Cumm) was 9500 (720016000) (Range: 3200-26000), median (IQR) Neutrophil (%) was 64 (54-71) (range: 14-90), median (IQR) Lymphocyte (%) was 28 (22-36) (range: 6-74) and median (IQR) Platelet count (/Cumm) was 200000 (172500284000) (Range: 40000-418000). Raised CRP, D-Dimer and S. Ferritin level were found among 43 (75.4%), 8 (14.4%) and 38 (66.7%) patients respectively. Available CXR findings of 47 patients showed that, 21 (45%) had patchy opacity, 19 (40%) had no significant abnormality and 6 (13%) had bilateral consolidation. Paracetamol was the most frequently (83.2%) used drug for this infection. Oral antibiotic was used in 64.2% children, bronchodilator and zinc supplementation were given to 48.4% and 43.2% children respectively. Oxygen therapy was needed for 12.6% children. More than half (57.7%) of the patients reported to feel fatigue after COVID-19 infection. About 40.4% patients had shortness of breath, 38.5% patients had history of weight loss. And 25% patients had lost their taste/smell.   Conclusion: Clinical presentations of COVID-19 in children were mild. Fever and cough were found to be the predominant symptoms of COVID-19 affected children in this study. Vomiting, nasal congestion and altered smell were also typical symptoms. Raised CRP and S. Ferritin level were two important laboratory findings. JCMCTA 2022 ; 33 (1) : 124-131

Introduction: Severe acute malnutrition (SAM) is an important cause of death in children. Bangladesh has a huge burden of SAM in under-five children, but documentation of their protocolized management and outcome is not so frequent. Objective: Our aim was to identify the pattern of the nutritional outcome and growth monitoring of 0-59 months old children with severe acute malnutrition treated with identified medical complications where the presence or absence of edema is an important clinical factor. Methods: This was a facility-based retrospective observational study that was conducted in the Severe Acute Malnutrition block of Chittagong Medical College Hospital, Chittagong. Here, a total of 485 patients were admitted during the period from 2013 to 2017. Based on WHO & National guidelines, admission and discharge criteria were considered and determined. A structured and prescribed data format was prepared and data were collected from the hospital records. Daily clinical follow-ups and weight monitoring of the patients were also documented. Both descriptive and analytic analyses were executed. After Data collection, it was cleaned, edited, and stored in excel, epi-INFO, and analyzed by SPSS. P-value < 0.05 was considered to be statistically significant. Results: 54.84% of the admitted patients were cured and discharged during the study period. The mean age of the observed patients was 22.35 ± 15.8607 months. The majority of the patients came from rural areas and about 50% of them belonged to lower-middle-class families. The median weight gain of the children at SAM block during the clinical review was found to be mod-How to cite this paper:

Background: Dengue outbreaks are hitting different geographic locations, different clinical manifestations are being reported recently. This study was aimed to describe the clinico-epidemiological profile and outcome of dengue infected children during 2019 dengue outbreak in Chattogram. Materials and methods: This hospital based prospective observational study was carried out in the Department of Pediatrics in Chattogram Medical College Hospital. Serologically positive dengue cases (Aged £12 years) admitted from July 2019 to December 2019 were enrolled in the study. Hospital outcome of the patient’s was recorded in terms of mortality, Length of Hospital Stay (LOS) need for ICU. Results: Out of total 192 patients as per the National Guideline 66.7% cases were classified as dengue fever without warning signs, 21.9% as dengue fever with warning signs and 11.5% as severe dengue. Overall the mean age was 7.04 (±3.23) years with male preponderance (59%). Along with fever main complaints were abdominal pain (91.7%), vomiting (47.9%) and headache (23.6%). Marked thrombocytopenia (Below 50,000) was present in 37.9%, leucopenia in 27.9% and raised haematocrit in 10.9% of cases. Average LOS was 5.2 (±1.9) days, 18 (9.5%) patients need ICU admission and there was no fatality in this series. Some clinical (Vomiting, flusihing, shock, reduced urinary output) and laboratory (Marked thrombocytopenia, leucopenia, hemoconcentration, pleural effusion and hepatomegaly) variables were associated with severity. Conclusion: Fever with abdominal pain were common presentations of dengue fever. Severe dengue patients presented with vomiting, flashing and shock. Marked thrombocytopenia and pleural effusion and/or ascites were related to shock. Appropriate and timely management is very effective in reducing case fatality. Chatt Maa Shi Hosp Med Coll J; Vol.20 (1); January 2021; Page 46-50