Introduction: Vitamin D deciency and insufciency have been associated with a variety of adverse maternal and fetal outcomes, ranging from Gestational hypertension, preeclampsia, gestational diabetes, preterm delivery, intrauterine growth restriction, and cesarean section. The study was done to determine whether vitamin D deciency in pregnant women was associated with complications. Methods: In this prospective observational study, vitamin D levels were estimated in 100 pregnant women from gestational age 32 to 40 weeks in a teaching hospital in Delhi, India. All the subjects were further followed up for the appearance of pregnancy associated complications mostly focusing on the appearance of Gestational Hypertension, Pre-eclampsia, Gestational Diabetes, IUGR, Preterm labour or landing up in Caesarean section. Results: 84% had suboptimal vitamin D level i.e serum vitamin D < 30ng/ml. Common complications were gestational hypertension (47%), caesarean section (47%) and gestational diabetes (41%). Signicantly low vitamin D levels were found in women with obstetric complications as compared to controls with no complications. Also, signicant association was found between suboptimal vitamin D levels and complications. Conclusion: The routine measurement of vitamin D in pregnancy can be of great help in identifying patients at risk for development of these complications, early intervention and prevention of occurrence of these complications. Cost effective and timely treatment can prevent the complications in expecting mothers

Background: Polycystic ovary syndrome (PCOS) is the most common endocrine disorder of reproductive age women. It is associated with dyslipidemia and Insulin resistance which is a high risk factor for cardiovascular disease in the long-term. Objectives:Aim of study to determine Insulin Resistance, lipid prole, ApolipoproteinA1 and Apolipoprotein- B levels in women with polycystic ovary syndrome. Study Design: Hospital based observational case control study. Method: We evaluated 80 polycystic ovary syndrome women as cases and age matched 80 women as controls visited to obstetrics and gynaecology OPD at NDMC Medical College and Hindu Rao Hospital, Delhi, India. The case selection was done according to Revised Rotterdam criteria (2003). Lipid parameters, Apo lipoprotein -A & Apo lipoprotein -B. Fasting blood sugar and fasting Insulin were measured. Insulin resistance (IR) was calculated by the HOMA-IR formula. Results: The present study showed signicantly higher values of triglycerides ( 48%) , HDL-C(46.95 ± 10.21mg% ) ,fasting glucose (25%) and IR (10 %)in case than control (8%, 41.78 ± 9.71 mg% , 7% and 5% respectively) and signicantly low value of Apo lipoprotein-A (45%) in PCOS women than controls (1.25%).Whereas the values of Total cholesterol, LDL-C, VLDL-C, Apolipoprotein B, fasting insulin ,TC/HDL and LDL/HDL ratios was not signicantly different between two groups. Conclusion: In the present study PCOS women had hypertriglyceridemia and raised IR whereas Apo lipoprotein -A was found low. These parameters are considered as high risk factors for cardiovascular disease. Early and regular screening of PCOS women can prevent progression of cardiovascular diseases.