The study was aimed to detect and characterize meteorological drought risk areas using remote sensing data in North Wollo, Ethiopia. Climate Hazards Group InfraRed Precipitation with Stations (CHIRPS) rainfall estimate was used to compute Z-Score Index (ZSI) and depict droughts during the meher season (2000 -2019). MOD13Q1 from Moderate Resolution Imaging Spectroradiometer (MODIS) image datasets was also used to generate Land Surface Temperature (LST) to investigate its association and trend with ZSI and the precipitation. To analyze the seasonal and annual rainfall trend, Mann-Kendal (MK) test was applied, and Sen's slope estimator was used to fix the magnitude of change. The MK test result revealed that an increasing trend of total annual rainfall (1.2 -10.7 mm year -1 ) has been observed in many districts, while the kiremt season showed a decreasing trend (-0.43 to -3.85 mm year -1 ). However, the belg (0.05 -0.23 mm), and bega (0.54 -2.80 mm) seasons revealed a slightly increasing trend in some districts.