For a long time the human being used plants to cover some of their nutritional needs, thanks to this for years some medicinal plants have been taken into account for the cure of diseases as an alternative to antibiotics Currently it is known that through food different types of foodborne diseases (ETA's) are obtained, these constitute an important public health problem in the regions, with social, economic, political and cultural implications.The microbiological analysis of the collected samples was carried out according to the standards established in the methodology of the Official Mexican Standard NOM-113-SSA1-1994, Method for counting total coliform microorganisms and the Official Mexican Standard NOM-031-SSA1-1993. The resistance profiles were carried out following the Kirby Bauer methodology. For theextract preparation and antimicrobial activity: the methodology described by Tirado torres et al., 2019.(67%), Cobaltin and Cefotaxime (50%) was followed. Low microbial activity was observed using the sea grape aqueous extract with inhibition halos of 8mm and 9mm.