Anthocyanins (ACNs) are plant secondary metabolites from the flavonoid family. Red to blue fruits are major dietary sources of ACNs (up to 1 g/100 g FW), being cyanidin-3-O-glucoside (Cy3G) one of the most widely distributed. Cy3G confers a red hue to fruits, but its content in raspberries and strawberries is low. It has a good radical scavenging capacity (RSC) against superoxide but not hydroxyl radicals, and its oxidative potential is pH-dependent (58 mV/pH unit). After intake, Cy3G can be metabolized (phases I, II) by oral epithelial cells, absorbed by the gastric epithelium (1%-10%) and it is gut-transformed (phase II & microbial metabolism), reaching the bloodstream (<1%) and urine (about 0.02%) in low amounts. In humans and Caco-2 cells, Cy3G's major metabolites are protocatechuic acid and phloroglucinaldehyde which are also subjected to entero-hepatic recycling, although caffeic acid and peonidin-3-glucoside seem to be strictly produced in the large bowel and renal tissues. Solid evidence supports Cy3G's bioactivity as DNA-RSC, gastro protective, anti-inflammatory, anti-thrombotic chemo-preventive and as an epigenetic factor, exerting protection against Helicobacter pylori infection, age-related diseases, type 2 diabetes, cardiovascular disease, metabolic syndrome and oral cancer. Most relevant mechanisms include RSC, epigenetic action, competitive protein-binding and enzyme inhibition. These and other novel aspects on Cy3G's physical-chemistry, foodomics, and health effects are discussed.

Arsenic is a metalloid frequently found in contaminated sites, especially in the soil. In this regard, soil contamination has attracted researchers’ attention because it affects soil suction, which is essential in unsaturated soil mechanics. Due to its reliability and low cost, the filter paper method is frequently used to evaluate soil suction. However, it is laborious and time consuming. As an alternative, different mathematical models have been developed to estimate natural soil’s suction. The objective of this study was to elucidate if Fuentes’ model (using fractal, Mualem, and Burdine restrictions) can be used to estimate the soil-water retention curve of an arsenic-contaminated soil by comparing it with the filter paper method data already reported. The results showed that under natural conditions, Fuentes’ model provided similar results to those obtained by the filter paper method. The model also suggested modification of the soil’s structure, observed by the increase in the soil’s particle diameter after contamination. However, Fuentes’ model was observed to overestimate the suction values for contaminated soils. This observation highlights the necessity to use a soil stabilization method to control the soil’s volume variations. The data also showed that Fuentes’ model overestimated the hydraulic conductivity function of the contaminated soil. Hence, the retention potential does not reflect the behavior of the contaminated soils and can induce misinterpretation of contaminant transport evaluation in soil. Nevertheless, further analyses should be performed to investigate the direct applicability of this model to soils contaminated with other substances.