Cardiopulmonary exercise testing (CPET) is a useful tool to test the physiological response of the cardiovascular, pulmonary and metabolic systems to exercise. Various parameters have previously been recognised as important to predict prognosis, and many of them show correlations with health outcomes. 1,2 The simplest measures are peak work rate, heart rate (HR) increase during exercise and its decline during the recovery phase. The highest obtained HR during exercise (HR peak) is related to the chronotropic competence of the heart. Especially in children, beyond moderate intensity exercise there is a strong correlation between HR and work rate. The recovery of HR after the cessation of exercise is mainly driven by the parasympathetic part of the autonomic nervous system. 3 In different studies this parameter is strongly related to outcome and prognosis. When a respiratory gas analysis system is available, ventilation (VE), oxygen uptake (VO 2) and carbon dioxide production (VCO 2) can be measured continuously. Subsequently, parameters such as maximal oxygen uptake (VO 2max), VE/ VCO 2 slope and the oxygen uptake efficiency slope (OUES) can be obtained.
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