High postprandial blood triglyceride (TG) levels increase cardiovascular disease risk. Exercise interventions may be effective in reducing postprandial blood TG. The purpose of this study was to determine the effects of sprint interval cycling (SIC), with and without replacement of the energy deficit, on postprandial lipemia. In a repeated-measures crossover design, six men and six women participated in three trials, each taking place over 2 days. On the evening of the first day of each trial, the participants either did SIC without replacing the energy deficit (Ex-Def), did SIC and replaced the energy deficit (Ex-Bal), or did not exercise (control). SIC was performed on a cycle ergometer and involved four 30-s all-out sprints with 4-min active recovery. In the morning of day 2, responses to a high-fat meal were measured. Venous blood samples were collected in the fasted state and at 0, 30, 60, 120, and 180 min postprandial. There was a trend toward a reduction with treatment in fasting TG (P = 0.068), but no significant treatment effect for fasting insulin, glucose, nonesterified fatty acids, or betahydroxybutryrate (P > 0.05). The postprandial area under the curve (mmol·l(-1)·3 h(-1)) TG response was significantly lower in Ex-Def (21%, P = 0.006) and Ex-Bal (10%, P = 0.044) than in control, and significantly lower in Ex-Def (12%, P = 0.032) than in Ex-Bal. There was no treatment effect (P > 0.05) observed for area under the curve responses of insulin, glucose, nonesterified fatty acids, or betahydroxybutryrate. SIC reduces postprandial lipemia, but the energy deficit alone does not fully explain the decrease observed.

The purpose of this study was to determine the influence of sprint interval cycling (SIC) on postprandial lipemia (PPL) and whether the replacement of the energy deficit created by SIC influences the reduction in PPL. Twelve healthy subjects, 6 men and 6 women, participated in 3 trials each taking place over 2 days. On the evening of the first day of each trial, the subjects either did SIC without replacing the energy deficit (Ex-Def), did SIC and replaced the energy deficit (Ex-Bal), or did not exercise (Con). In the morning of the second day, subjects ate a highfat meal. Venous blood samples were collected in the fasted state and then at 0, 30, 60, 120, and 180 minutes postprandial. There was no significant difference in fasting TG concentrations (P > 0.05). The postprandial area under the curve (AUC) (mmol·l -1 ·3 h -1 ) TG response was significantly lower in Ex-Def (21%, P = 0.006) and Ex-Bal (10%, P = 0.044) compared to Con.Ex-Def was significantly lower (12%, P = 0.032) compared to Ex-Bal in postprandial AUC TG response. Incremental TG AUC response did not differ among the treatments, suggesting the reduction in TG AUC was associated with lower fasting TG concentrations. The results indicate that SIC reduces PPL, in part, because of the energy deficit created.