Early guidance emphasizes the provision of information to families about growth and normal development in childhood such as specific information about security at home. This research aimed to analyze mothers' knowledge about the prevention of accidents in childhood before and after an educational intervention. It was conducted as a quasi-experimental study with 155 mothers in a Basic Health Unit in northeastern of Brazil in April and May of 2015. The data were collected in two stages through a self-report questionnaire performed before and after the educational intervention by the subjects. The results revealed a significant increase in knowledge about prevention of accidents in childhood in all the self-applied questions (p<0.05). After the educational intervention, there seemed to be a significant difference with the questions regarding the knowledge on preventing fall (p=0.000), drowning (p=0.000), and intoxication (p=0.007). The authors concluded that the educational intervention performed in this study increased the subjects’ knowledge on prevention of accidents in childhood.

(24,44%). Houve predomínio de casos no sexo masculino (51,06%), cor parda (55,65%), faixa etária de 10-14 anos (60,22%) e com escolaridade média de 6-11 anos (59,8%). A maioria das formas clínicas notificadas foi do tipo indeterminada (40,13 %), tendo como predominante o grau de incapacidade física II (21,1 %). Não foram estatisticamente significantes as diferenças proporcionais entre as formas clínicas (p-valor=0,056); ao passo que a escolaridade apresentou associação significativa (p<0,0001) com a ocorrência da doença entre menores de 15 anos de idade. Conclui-se que a hanseníase continua uma doença de fácil disseminação, considerando a frequência de casos novos. PALAVRAS-CHAVE: Hanseníase. Incidência. Menores de 15 anos. INCIDENCE OF LEPROSY IN PATIENTS AGED 15 OR YOUNGER CARED IN THE MUNICIPALITY OF IMPERATRIZ, MARANHÃO, BETWEEN 2004 AND 2010ABSTRACT: The purpose of this study was to estimate the global incidence and cases indexes of leprosy and to design the socio--demographic profile in children under 15 years of age in the municipality of Imperatriz, in the state of Maranhão, Brazil. A longitudinal retrospective study of leprosy cases in the municipality was performed, using information generated by the disease reports in SINAN NET. There was a predominance of male (51.06%), brown color (55.65%), aged between 10-14 years (60.22%), and average schooling of 6-11 years (59.8%). Most of the clinical forms reported were of the indeterminate type (40.13%), with predominance of physical incapacity degree II (21.1%). The proportional differences between the clinical forms (p-value = 0.056) were not statistically significant, while schooling presented a significant association (p <0.0001) with the occurrence of the disease among children under 15 years of age. It can be concluded that leprosy remains a disease with easy spread when considering the rate of new cases.

Background. Leprosy is an infectious disease that can lead to physical disabilities and stigmatization. It remains an important public health problem, especially in Brazil. Objective. To analyse sociodemographic and clinical factors associated with multibacillary leprosy in a hyperendemic region of the disease in northeastern Brazil. Method. This is a retrospective observational study with secondary data acquired from 2012 to 2015, from a group of leprosy cases reported in a reference outpatient clinic for the treatment and followup of leprosy in the city of Imperatriz, Maranhao, in northeastern Brazil. Results. From 905 new cases of leprosy studied, 656 (72.5%) were classified as multibacillary leprosy and 249 (27.5%) as paucibacillary leprosy. We observed that men were more likely to present 5 to 15 skin lesions (OR: 1.32; 95% CI: 1.18-1.49; p <0.0001) and >15 skin lesions (OR: 1.26; 95% CI: 1.09 -1.45; p = 0.005) and a lower chance of having <5 skin lesions (OR: 0.67; 95% CI: 0.59-0.76; p <0.0001). Women were more likely to have no affected nerves compared to men (OR: 1.46; 95% CI: 1.20-1.77; p <0.0001). The age range of 16 to 60 years showed a greater chance of having <5 skin lesions (OR: 1.01; 95% CI: 1.007-1.20; p = 0.03) and a lower chance of having 5 to 15 skin lesions (OR: 1.12, 95% CI: 1.03-1.23; p= 0.008) and a lower chance of being a grade I disability ( CI= 0.73-0.94; p=0.83) and II (OR: 0.82; 95% CI: 0.77-0.98; p=000.1). Conclusion. Cases of multibacillary leprosy were associated with male gender, low educational level, and clinical variables such as number of skin lesions and grade I or II disability.

The monitoring and combined use of dietary supplements to restore adequate growth are paramount and highly recommended in child malnutrition, an important public health problem. The objective of this study was to analyze the effects of cashew nut seed flour in children with moderate malnutrition, treated at primary healthcare services. This is a randomized clinical trial conducted from April to October 2017 in the city of Imperatriz, Brazil. The sample comprised 30 children born at term, aged between 2 and 5 years, and newly diagnosed with malnutrition (60 days or less), randomized into experimental and control groups. The intervention consisted of daily intake of cashew nut seed flour. There was intragroup statistically significant difference in the glucose levels of children who were assigned to the control group (p=0.02) and in the glycated hemoglobin in the experimental group (p<0.01). Intergroup analysis of glycated hemoglobin levels showed statistically significant differences in favor of the experimental group (p=0.01). HDL and LDL had, respectively, increased and decreased in the experimental group. The use of cashew nut seed flour in a 24-week period had positive effects on glycated hemoglobin, HDL, and LDL parameters in moderately malnourished children.

Background: Incorporating spatial approaches into epidemiological research is a challenge in public health research. The goal in this study was to analyze the spatial distribution of cases of deaths by tuberculosis in Imperatriz -MA (Brazil) and to characterize these events according to sociodemographic and operational characteristics. Methods and Findings:In this ecological study, all deaths from tuberculosis as the primary causeregistered in the Mortality Information System from 2005 to 2014 were considered. The research variables were subject to descriptive analysis, point density analysis (Kernel Intensity Estimation) and area analysis.Fifty cases of deaths by TB were identified, particularly the pulmonary clinical form. Male patients were predominant, with a median age of 59 years, mulatto race/color, single, who had finished secondary education. Most deaths happened at the hospital, with medical care before death and without autopsy. Most events happened at the hospital, with medical care delivery by an assistant physician and without autopsy. The point density revealed heterogeneity in the spatial distribution of the deaths, with rates of up to 2.33 deaths/km 2 . The