Background: new minimally invasive sternotomy (mini-sternotomy) procedures have improved the treatment outcome and reduced the incidence of perioperative complications leading to improved patient satisfaction and a reduced cost of aortic valve replacement in comparison to the conventional median sternotomy (full sternotomy). The aim of this study is to compare and gain new insights into operative and early postoperative outcomes, long-term postoperative results, and 5-year survival rates after aortic valve replacement through a ministernotomy and full sternotomy. Methods: This is a retrospective study of patients who underwent an isolated replacement of the aortic valve via a full sternotomy or ministernotomy from 2011 to 2016. From 2011 to 2016, 426 cardiac interventions were performed, 70 of which (16.4%) were of the ministernotomy and 356 (83.6%) of the full sternotomy. Through propensity score matching, 70 patients who underwent the ministernotomy (ministernotomy group) were compared with 70 patients who underwent the full sternotomy (control group). Results: in the propensity matching cohort, no statistical difference in operative time was noted (p = 0.856). The ministernotomy had longer cross clamp (88.7 ± 20.7 vs. 80.3 ± 24.6 min, p = 0.007) and bypass (144.0 ± 29.9 vs. 132.9 ± 44.9 min, p = 0.049) times, less ventilation time (9.7 ± 1.7 vs. 11.7 ± 1.4 h, p < 0.001), shorter hospital stay (18.3 ± 1.9 vs. 21.9 ± 1.9 days, p = 0.012), less 24-h chest tube drainage (256.2 ± 28.6 vs. 407.3 ± 40.37 mL, p < 0.001), fewer corrections of coagulopathy (p < 0.001), fewer patients receiving catecholamine (5.71 vs. 30.0%, p < 0.001) and better cosmetic results (p < 0.001). Moreover, the number of patients without complaints at 1 year after the operation was significantly greater in the ministernotomy group (p = 0.002), and no significant differences in the 5-year survival between the groups were observed. In the overall cohort, the ministernotomy had longer cross clamp times (88.7 ± 20.7 vs. 79.9 ± 24.8 min, p < 0.001), longer operative times (263.5 ± 62.0 vs. 246.7 ± 74.2 min, p = 0.037) and bypass times (144.0 ± 29.9 vs. 132.7 ± 44.5 min, p = 0.026), lower incidence of 30-day mortality (1(1.4) vs. 13(3.7), p = 0.022), shorter hospital stays post-surgery p = 0.025, less 24-h chest tube drainage, p < 0.001, and fewer corrections of coagulopathy (p < 0.001). Conclusions: the ministernotomy has a number of advantages compared with the full sternotomy and thus could be a better approach for aortic valve replacement.
Ligoniai ir metodai58 ligoniai (amþiaus vidurkis 66 metai), NYHA III-IV funkcinës klasës, suskirstyti á dvi grupes. Pirmoje grupëje (19 ligoniø) taikyta pastovi retrogradinë drungno kraujo kardioplegija, antroje (39 ligoniai) -antegradinë frakcinë drungno kraujo kardioplegija.Aortos perspaudimo laikas 93 ± 5 min. Abiejø grupiø ligoniams buvo vertinamas savaiminis ðirdies veiklos atsikûrimas po aortos atleidimo, EKG normalizavimosi laikas, trukmë nuo aortos atleidimo iki dirbtinës kraujo apytakos sustabdymo, adrenomimetikø poreikis pirmà pooperacinae parà, echoskopinis kairiojo skilvelio funkcijos ávertinimas prieð operacijà ir po jos. RezultataiIðgyveno 54 ligoniai, mirë 4 (po 2 ið abiejø grupiø). Vienas ligonis mirë nuo smegenø paþeidimo, du nuo dauginio organø nepakankamumo ir vienas nuo ðirdies silpnumo. Buvo geresni visø vertinamø tyrimø antros ligoniø grupës rezultatai (1 lentelë). IðvadosTrijø ðirdies voþtuvø korekcijos operacijose miokardo apsaugai tinkama naudoti tiek pastovi retrogradinë drungno kraujo kardioplegija, tiek frakcinë antegradinë drungno kraujo kardioplegija. Kiek geresni buvo antros ligoniø grupës rezultatai. Pagrindiniai þodþiai: kardioplegija, voþtuvø korekcija
TikslasAnalizuoti rizikos veiksniai 221 ligonio, kuriam atlikta kylanèiosios aortos aneurizmos esant aortos voþtuvø nesandarumui, korekcija konduitu. Ligoniai ir metodaiDarbas atliktas Vilniaus universiteto Ðirdies chirurgijos centre. Ligoniai stebëti nuo vieno mën. iki 20 metø po operacijos. Pacientai tirti suskirstyti á ðias tris grupes pagal klinikinae eigà:• 1 grupë -ûminë sluoksniuojanèioji kylanèiosios aortos aneurizma (ÛSA) -48 (21,7%) ligoniai, vidutinë simptomø atsiradimo trukmë -0,25 ± 0,11 mën.• 2 grupë -lëtinë sluoksniuojanèioji kylanèiosios aortos aneurizma (LSA) -44 (19,9%) ligoniai, vidutinë simptomø atsiradimo trukmë -24,4 ± 5,26 mën.• 3 grupë -lëtinë nesisluoksniuojanèioji kylanèiosios aortos aneurizma (LNA) -129 (58,4%) ligoniai, vidutinë simptomø atsiradimo trukmë -44,6 ± 5,06 mën.Prieðoperacinë vidutinë funkcinë klasë (f. kl.) (NYHA) klinikinëse grupëse atitinkamai buvo: 4,5 ± 0,08; 4,0 ± 0,12 ir 3,5 ± 0,05. RezultataiIðskirta 14 (p < 0,01) reikðmingø rizikos veiksniø, turëjusiø átakos ligoniø iðgyvenimui -amþius, ligos trukmë, prieðoperacinë funkcinë klasë, skausmas uþ krûtinkaulio, ðokas, prieðoperacinis miokardo infarktas Q+, KSdd, KSH, sistolinis arterinis kraujospûdis, DKA trukmë, galvos smegenø kraujotakos nepakankamumas, kairiojo skilvelio iðmetimo frakcija, kylanèiosios aortos skersmuo. Koreliacinë analizë parodë, kad yra glaudus tiesinis prieðoperacinës f. kl. ir DKA trukmës -r = 0,374 (p = 0,01) ryðys.
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