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Background: Counterfeit drugs are a global problem and suffered almost all developing and developed countries worldwide. In India, it is a major problem which results life threatening issues as well as financial loss on health system. So, we conducted a cross sectional questionnaire-based study on knowledge and exposure to counterfeit drugs of doctors at SHKM Govt. Medical College, Nuh, Haryana, India.Methods: A structured questionnaire was distributed to 100 registered doctors. The questionnaire was based on knowledge, attitude and its consequence on the heath system by the practices of counterfeit medication.Results: There were Twenty questionnaires excluded from the study due to incomplete information. Only 57.77% (46/80) subjects having the knowledge of questionnaire correct meaning of counterfeit drug. However, almost 90% (72/80) subjects were aware about its dangerous effects. More than 50% of the subjects have suggested that modern technology is capable to control counterfeiting of the medicine.Conclusions: Counterfeit drugs create a people health hazard and waste to consumer income. The proper knowledge, awareness and modern technological approaches are the devices may helpful in diminution of counterfeit medication practices.

In Chronic inflammatory and painful diseases, such as Osteoarthritis, Rheumatoid arthritis, Low back pain, Fibromyalgia drugs that are currently used for the treatment of pain are opioids and for inflammatory conditions are non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. All these drugs produce potential toxic effects. Apigenin, a naturally occurring plant flavone, abundantly present in common fruits and vegetables, is recognized as a bioactive flavonoid. Current study envisaged analgesic properties of apigenin in animal models. Three dose, 10mg/kg,20mg/kg and 40mg/kg of apigenin were used in this study. Analgesic activity was studied in rat and mice by radiant tail-flick and Eddys hot plate models respectively. In both models the standard drug used was Tramadol-25mg/kg. The optimal analgesic effect of apigenin can be seen at dose 20mg/Kg in tail-flick(P<0.05) and Eddy’s Hot plate model (P<0.05) in comparison to control and standard drug respectably. In conclusion Apigenin processes analgesic activities.

Background: Rational use of drugs had been great concern by the government as well as public during the past several years. Monitoring of prescriptions studies could identify the associated problems and provide feedback to the prescribers, so as to create awareness about the irrational use of drugs. This study was conducted to evaluate the prescribing pattern of Vitamins/Tonics in government sector and private sector.Methods: This prospective study was designed to obtain statistical data on the prescribing pattern of Vitamins/tonics in patients of S.V.B.P. Hospital Meerut and other associated hospital/ clinics. The total study sample size was of 614 prescriptions. Out of these 439 prescriptions were from government sector, 175 prescriptions from private sectors.Results: Percentages of prescription with Vitamins/ Tonics were 35.76 and 48.57 in government and private sectors respectively and these differences are statistically significant. Percentage of drug prescribed as Vitamins/ Tonics of the total drugs was 8.68 and 10.19, in government and private sector respectively and these differences are statistically not significant. Vitamins/ Tonics were the most frequently prescribed drugs 16.52% and 17.14% in obs./ Gynae in both the sectors respectively, and least number of Vitamins/ Tonics 1.06% and 3.2% were prescribed in cardiology in both the sectors.Conclusions: The study indicates a big scope for enhancing the prescribing pattern of Vitamins/Tonics and minimizing the use of irrational Vitamins/Tonics, due to the fact most of the times it’s not needed, and it only put financial burden on Patients.