Gastric cancer (GC) incidence has not declined in Mexico.We assessed whether the intake of capsaicin (CAP), the pungent compound of chili peppers, increases the risk of GC independently of H. pylori positivity (Hp). From 1994 to 1996, a hospital-based case-control study was performed in 3 areas of Mexico; 234 cases of GC and 468 matched controls were enrolled and their diet and other characteristics were inquired. Chili pepper intake was queried by interview and CAP content of chilies was determined in a separate analysis by gas chromatography to estimate CAP intake; IGg Hp serum antibodies were determined by ELISA. The risk of GC was increased (OR ‫؍‬ 1

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This paper presents an assessment of alcohol consumption, including the popular Mexican liquor tequila, in relation to the incidence of gastric cancer. We conducted a population-based case-control study in Mexico City (OR = 2,93; I.C. 95% 1,75), p<0,05. Essa associação persistiu tanto para os tumores de tipo intestinal (OR = 2,16; I.C. 95% 0,92, p de tendência 0,031), quanto para os de tipo difuso (OR = 4,48; I.C. 95% 1,94, p de tendência 0,018). O consumo de cerveja e bebidas destiladas (conhaque, rum, tequila) não esteve associado com maior risco de CG.