than in the control group. In the formalin test, the licking time for THME at doses of 300 and 500 mg/kg was significantly shorter ( p < 0.001) compared to the control group in the first phase of the formalin test, whereas in the second phase only the dose of 500 mg/kg showed an antinociceptive effect. In addition, THME at doses of 300 and 500 mg/kg significantly increased the latency time in the tail flick test ( p < 0.05 and p < 0.001, respectively) and in the hot plate test ( p < 0.01 and p < 0.001, respectively) compared to the control group. Conclusions: These results show that THME had antinociceptive activity using several models of nociception, and they suggest that the effect is mediated by the participation of both peripheral and central antinociceptive mechanisms. AbstractObjective: The aim of this study was to evaluate the antinociceptive activity of the methanol extract of Tabebuia hypoleuca stems (THME). Materials and Methods: The animals were divided into 5 groups of 8 mice for each test (negative controls, positive controls, and 3 groups treated with THME at doses of 150, 300, and 500 mg/kg, p.o.). The antinociceptive effect of THME was evaluated using the writhing, formalin, tail flick, and hot plate models in mice. Results: In the writhing test, THME (150, 300, and 500 mg/kg) produced significantly ( p < 0.001) fewer writhes induced by acetic acid Significance of the Study• In this study Tabebuia hypoleuca was shown to have antinociceptive effects mediated by the participation of both peripheral and central antinociceptive mechanisms. The T. hypoleuca species could become a new therapeutic option for the treatment of pain.
In order to obtain taro flour and make breads, tubers were purchased in the vicinity of the Santo António neighborhood in the Huambo, which were transported in polyethylene bags and subsequently cleaned in running water, peeled by hand with a knife, sanitized with acidified water with lemon and cut into pieces, then proceeded to dry directly in the sun and after seven days they were crushed in a traditional mortar, subsequently the sifting was carried out, then it was packed and kept in a refrigerator for late use, from this process the white colored flour was obtained that served for the preparation of breads, this products with different levels of inclusion were constituted in formulations of 30% and 50%, all presented attributes considered acceptable when reaching acceptability scales greater than 4 points with the exception of the softness attribute in the formulation of 100% taro which reached only 3.93 points.
Con el objetivo de determinar el efecto antihelmíntico de la especie Tephrosia vogelii sobre estrongílidos gastrointestinales de caprinos, se recolectaron hojas de la planta y se obtuvo un extracto bruto. Treinta caprinos infectados naturalmente se dividieron en tres grupos de diez animales cada uno. Grupo I (control) al cual se le administraron 50 ml de agua destilada; grupo II, al que se les administró una dosis diaria del extracto de 100 mg/kg, y grupo III, que recibió una dosis diaria del extracto de 150 mg/kg. El tratamiento se realizó oralmente por tres días consecutivos. Los conteos de huevos en mostraron que los animales presentaban una parasitosis gastrointestinal compuesta de los géneros Haemonchus spp. Trichostrongylus spp. y Oesophagostomum spp., siendo Haemochus spp. el de mayor proporción (75 %). La reducción de los conteos de huevos fue del 91 % y el 94 % para los grupos II y III, respectivamente, a los 14 días postratamiento.
With the aim of determining some bromatological parameters of moringa from two different locations and at the same period of the year, fresh leaves were collected and air-dried, and then ground to be converted into powder. This was passed through a sieve, packaged and sent to the Central Laboratory for Food and Agriculture in Luanda in order to determine the content of crude protein, crude fibre, ether extract and vitamin C. The evaluation of dry matter, moisture, ashes and carbohydrates was carried out at the Centre for Research and Agro-Food Technology of the Faculty of Veterinary. Both samples showed promising and varied bromatological contents, having the moringa from Cubal presented the following values: crude protein-22.33%, crude fibre-0.14%, ether extract-10.54% and carbohydrate 47.43%, while in the moringa from Sumbe the crude protein was 24.72%, crude fibre 0.24%, ether extract 5% and carbohydrate 52.65%.
Plant species Croton mubango Müll Agr. and Indigofera hendecaphlla Jacq. they are traditionally used in various diseases in animals and humans in the province of Huambo, Angola. The objective of the present work was to determine the phytochemical composition of methanolic extracts of leaves of said species. The samples to be studied were collected in several places of Comuna Comandante Nzaji in the municipality of Huambo, in the rainy period. They were dried, milled and transferred to the National Center for Agricultural Health (Cuba) for phytochemical screening. The main groups found were primary and secondary aminos, free phenols, tannins, triterpenes and / or steroids and alkaloids. The primary and secondary amino compounds, free phenols, tannins and alkaloids were found in high amounts in the leaves of I. hendecaphlla and for C. mubango were found in this same amount in addition to amines the triterpenes and / or steroids since phenols and alkaloids They were presented in moderate quantity and tannins in a mild way. It is concluded that the methanolic extracts of the plants evaluated present secondary metabolites in moderate to high concentrations. The metabolites found in these two plant species are of biological and pharmacological interest for their possible therapeutic applications in both animals and humans.
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