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Resveratrol is a potential bioactive compound found in fruits and taken as dietary supplements. Due to possessing multiple beneficial properties;anti-oxidant, anti-atherosclerosis, cardioprotective, anti-cholesterolemia and glucose regulation. It combats with globally high mortality and morbidity rate diseases. Resveratrol deals with cardiovascular disease and other associated diseases after the result of ROS accumulation. It seems successful in neutraceutical and pharmaceutical to prevent and treat cancer proliferation, diabetes, diabetic-cardiomyocyte, neuropathy, nephropathy and obesity.