No abstract

! CAC cap-assisted colonoscopy CRC colorectal cancer EMR endoscopic mucosal resection ESGE European Society of Gastrointestinal Endoscopy FAP familial adenomatous polyposis FICE Fujinon intelligent color enhancement, flexible spectral imaging enhancement FAP familial adenomatous polyposis GRADE grading of recommendations assessment, development and evaluation HD-WLE high definition white-light endoscopy i-SCAN Pentax virtual chromoendoscopy system MAP MUTYH-associated polyposis NBI narrow band imaging PICO population, intervention, comparator, outcome PIVI preservation and incorporation of valuable endoscopic innovations RCT randomized controlled trial SD-WLE standard definition white-light endoscopy TER third eye retroscope WLE white-light endoscopy

No abstract

Confocal laser endomicroscopy is a newly introduced endoscopic tool that makes it possible to carry out confocal microscopic examination of the mucosal layer during ongoing endoscopy. Different types of tissue and diseases can be diagnosed immediately, facilitating early diagnosis of gastrointestinal cancer. Analysis of the in vivo microarchitecture is helpful in targeting biopsies to relevant areas. In addition, subsurface imaging can unmask microscopic diseases - (microscopic colitis) or bacterial infection ( HELICOBACTER PYLORI), for example. Molecular imaging is becoming feasible, and this will shortly open the door to new indications in gastrointestinal endoscopy (e.g., in vivo receptor analysis).

HD+ colonoscopy with I-Scan is superior to standard video colonoscopy in detecting patients with colorectal neoplasia based on this prospective, randomized, controlled trial.