See article by Cannatà et al., pages 37e44 of this issue.The role of sex differences in cardiovascular disease (CVD) has received considerable attention in recent years. These differences not only include diseases and risk factors unique to one sex, such as pregnancy-related cardiovascular changes in women, but also to common diseases and risk factors that differentially affect members of one sex. Epidemiological research confirms sex differences in the prevalence of risk factorsdsuch as hypertension, diabetes mellitus, obesity, dyslipidemia, and smokingdbetween men and women. [1][2][3][4] Women are also uniquely affected by endocrine conditions such as polycystic ovary syndrome; pregnancy-related hypertensive, diabetic, and placental disorders; as well as menopause, each of which have been found to increase the likelihood of either developing CVD or developing risk factors such as type 2 diabetes mellitus. 4 However, prognoses for women is typically more favourable than for men, as demonstrated by their lower rate of CVD mortality despite older age of onset and higher prevalence of absolute disease. 1,5 The multitude of physiological differences between men and women affected by CVD have been attributed to a complex interaction among genetic, hormonal, and environmental factors that include the cardioprotective effects of estrogen, as well as differences in body weight and fat proportion. 6,7 Differences may also be related to biases in clinical care; women receive fewer diagnostic investigations, are less likely to receive guidelinerecommended care, and receive less intensive care compared with their male counterparts. 3,8-10
Correction for ‘Toxicity of nanoencapsulated bifenthrin to rainbow trout (Oncorhynchus mykiss)’ by Tamzin A. Blewett et al., Environ. Sci.: Nano, 2019, 6, 2777–2785, DOI: 10.1039/C9EN00598F.
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