Indolent CD8+ lymphoid proliferation of the ear is a recently described cutaneous lymphoid proliferation that clinically presents with slow growing lesion(s) on the ear(s). In cases reported to date, there has been indolent clinical behavior and no evidence of systemic involvement. Characteristic histopathologic features include a non-epidermotropic diffuse dermal infiltrate of CD8+ T-lymphocytes with a lymphoblast-like appearance. T-cell clonality has also been observed. Herein, we present two patients who show clinical, histopathologic and immunophenotypic features similar to the original index cases described by Petrella et al. In addition, we review the literature regarding this unusual lymphoid proliferation and provide evidence that this entity represents a phenotypic variant of primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma, a concept proposed by Beltraminelli et al. in 2009. Differentiation between this lymphoproliferative process and other more aggressive CD8+ lymphomas is essential in avoiding excessive treatment of a condition that combines worrisome histopathology with indolent clinical behavior.
Florida's adverse event data do not show higher adverse event rates in physician offices compared with ambulatory surgical centers. Incident reporting and public availability of incidents are important, as is standardization of reporting rules for both adverse events and number of procedures performed in different settings.
The medical and legislative community should seek to scientifically examine office surgery. Overregulation or loss of office surgery would have a tremendous impact on the management of skin cancers and the delivery of quality cosmetic and laser surgery.
BACKGROUND. Office-based surgery has become an important method of health-care delivery, but there is controversy about its safety and which practitioners should perform it. Several states have already or are preparing to enact legislation regulating office-based surgery. OBJECTIVE. The objective was to discuss recent literature pertaining to the safety of office surgery and to discuss reasons why there are perceived differences in its safety. METHODS. The pertinent literature is reviewed.RESULTS. The majority of studies suggest that office surgery is safe. A recent study that found to the contrary may have methodologic flaws. CONCLUSION. The medical and legislative community should seek to scientifically examine office surgery. Overregulation or loss of office surgery would have a tremendous impact on the management of skin cancers and the delivery of quality cosmetic and laser surgery.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.