Research partnerships with northern communities hold promise for capacity and resilience against environmental changes. Given their historical ecological and cultural relationship with and, thus, ongoing concern for polar bears, Inuit communities are keen to participate in monitoring programmes. In spite of this, northern communities continue to meet polar bear research and collaborations with some resistance. Here, we summarise and report interviews with Nunavummiut from four communities on Inuit experiences with polar bears and research perspectives. Research interactions reveal ongoing cultural, socio-ecological and ethical barriers to polar bear research projects. Research licenses and standardised ethics procedures do not always guarantee collaborations. Adaptable research methods, mutual understanding and open dialogue are essential to form strong research partnerships with northern communities.