Aim:Report of our experience with topical feracrylum citrate to minimize hemorrhage-related complications in pediatric hypospadiac patients.Materials and Methods:One hundred and fifty consecutive pediatric hypospadiac patients over 3 years (75 in study group and 75 controls - random allocation) were studied. One hundred milliliter of 1% feracrylum citrate solution was used in study cases and equivalent normal saline in controls. The parameters assessed were frequency of cauterizations, intraoperative blood loss, wound edema and postoperative complications.Results:Average number of cauterizations was 1.55 per patient in study group and 5.7 per patient among controls. Among cases, average number of blood soaked gauge pieces was 3.56 per patient, correlating with average intraoperative blood loss of 17.8 ml. In controls, average blood soaked gauge pieces were 6.2 per patient corresponding to an average blood loss of 31 ml. Postoperative hematoma was seen in 8% cases compared with 18% controls. Wound edema appeared in 13.3% cases and 47% controls. Postoperative complications were higher among controls.Conclusions:Feracrylum is an effective and safe topical hemostatic agent to minimize significantly diffuse capillary oozing and surface bleeding. It reduced the frequency of cauterization and tissue damage, intraoperative blood loss, postoperative hematoma, wound edema and postoperative complications.

Background: Collagen is a fibrous structure, proline-rich protein, comprised of three α-chains, plays an important role in each stage of wound healing, attracts fibroblasts and keratinocytes which in turn encourages debridement, angiogenesis and re-epithelializationMethods: This is a prospective cohort study. After obtaining ethical clearance from Institute’s ethical committee, all the patients fulfilling inclusion criteria were enrolled and written consent was obtained from all the patients. Detailed history was enquired and recorded on a predesigned proforma. The ulcer healing, analysed as- Time required for appearance of healthy granulation tissue, 50% reduction in ulcer size, complete healing time, requirement of skin grafting, time required in return to daily activities.Results: A significant decrease in time required for 50 % reduction in wound size with a mean difference of 18.5 in collagen group patients when compared to 37.5 and 33.0 in Normal saline group patients and Povidone iodine group patients. Chi square test was applied to assess the difference in proportions between groups t test was applied to compare the mean between the groups. P<0.05 was considered as statically significant.Conclusions: Healing with collagen particles is early, compared to the conventional dressings with lesser requirement of skin grafting, number of dressings, shorter hospital stay. Dressing changed every 3-4 days. Healing occurs by formation of early granulation tissue and wound contraction.